Targeted Osmotic Lysis: A Novel Approach to Targeted Cancer Therapies
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DOI: 10.3390/biomedicines10040838
Abstract: The conventional treatment of cancer has been based on the delivery of non-selective toxins and/or ionizing energy that affect both the cancer and normal tissues in the hope of destroying the offending disease before killing… read more here.
Keywords: targeted osmotic; cancer; lysis novel; approach ... See more keywords
Involvement of Pore Formation and Osmotic Lysis in the Rapid Killing of Gamma Interferon-Pretreated C166 Endothelial Cells by Rickettsia prowazekii
Sign Up to like & getrecommendations! Published in 2022 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed7080163
Abstract: Rickettsia prowazekii, the bacterial cause of epidemic typhus in humans, proliferates mainly within the microvascular endothelial cells. Previous studies have shown that murine macrophage-like RAW264.7 cells are rapidly damaged if they are pretreated with gamma… read more here.
Keywords: osmotic lysis; gamma interferon; endothelial cells; formation ... See more keywords