Rice Nudix Hydrolase OsNUDX2 Sanitizes Oxidized Nucleotides
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DOI: 10.3390/antiox11091805
Abstract: Nudix hydrolase (NUDX) hydrolyzes 8-oxo-(d)GTP to reduce the levels of oxidized nucleotides in the cells. 8-oxo-(d)GTP produced by reactive oxygen species (ROS) is incorporated into DNA/RNA and mispaired with adenine, causing replicational and transcriptional errors.… read more here.
Keywords: osnudx2 gene; oxidized nucleotides; oxo dgtp; osnudx2 ... See more keywords