Osteopontin and the dento-osseous pathobiology of X-linked hypophosphatemia.
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DOI: 10.1016/j.bone.2016.11.019
Abstract: Seven young patients with X-linked hypophosphatemia (XLH, having inactivating PHEX mutations) were discovered to accumulate osteopontin (OPN) at the sites of defective bone mineralization near osteocytes - the so-called hallmark periosteocytic (lacunar) "halos" of XLH.… read more here.
Keywords: xlh; bone; dento osseous; linked hypophosphatemia ... See more keywords