Circular RNA triple functional domain promotes osteoarthritis’ development by modulating the microRNA-136-5p/Nicotinamide phosphoribosyltransferase axis
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DOI: 10.1080/21655979.2021.2018095
Abstract: ABSTRACT Numerous studies have affirmed the participation of circular RNA (circRNA) in osteoarthritis (OA)’ development. Previous studies have exposed the elevation of the circRNA triple functional domain (TRIO) in OA, while the molecular mechanism of… read more here.
Keywords: triple functional; circular rna; functional domain; osteoarthritis development ... See more keywords
Association between genetic polymorphisms and osteoarthritis development. Overview of systematic reviews
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DOI: 10.1111/1756-185x.14362
Abstract: To identify, critically evaluate and synthesize the evidence obtained from systematic reviews on the association between genetic polymorphisms and osteoarthritis (OA) development. read more here.
Keywords: systematic reviews; genetic polymorphisms; polymorphisms osteoarthritis; osteoarthritis development ... See more keywords
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway
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DOI: 10.1155/2022/2188145
Abstract: Purpose OA is a multifactorial joint disease in which inflammation plays a substantial role in the destruction of joints. Corynoline (COR), a component of Corydalis bungeana Turcz., has anti-inflammatory effects. Materials and Methods We evaluated… read more here.
Keywords: corynoline alleviates; development; development via; osteoarthritis development ... See more keywords
DL-3-N-Butylphthalide Promotes Cartilage Extracellular Matrix Synthesis and Inhibits Osteoarthritis Development by Regulating FoxO3a
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DOI: 10.1155/2022/9468040
Abstract: Osteoarthritis (OA) has been reported as a progressive disease in the elderly, primarily characterized by degenerated articular cartilage. There has been no satisfactory drug for the treatment of OA. DL-3-n-butylphthalide (NBP), a small molecule compound… read more here.
Keywords: extracellular matrix; cartilage extracellular; promotes cartilage; osteoarthritis development ... See more keywords