Osteoblast Lineage Support of Hematopoiesis in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4678
Abstract: In mammals, hematopoiesis migrates to the bone marrow during embryogenesis coincident with the appearance of mineralized bone, where hematopoietic stem cells (HSCs) and their progeny are maintained by the surrounding microenvironment or niche, and sustain… read more here.
Keywords: health disease; hematopoiesis health; hematopoiesis; osteoblast lineage ... See more keywords
Intracellular density is a novel indicator of differentiation stages of murine osteoblast lineage cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30135
Abstract: Osteoblasts are primary bone-making cells originating from mesenchymal stem cells (MSCs) in the bone marrow. The differentiation of MSCs to mature osteoblasts involves an intermediate stage called preosteoblasts, but the details of this process remain… read more here.
Keywords: density; osteoblast lineage; lineage cells; differentiation ... See more keywords
Loss of the PTH/PTHrP receptor along the osteoblast lineage limits the anabolic response to exercise
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DOI: 10.1371/journal.pone.0211076
Abstract: Exercise and physical activity are critical to maintain bone mass and strength throughout life. Both exercise and physical activity subject bone to a unique combination of stimuli in the forms of dynamic loading and a… read more here.
Keywords: pth; along osteoblast; osteoblast lineage; exercise ... See more keywords
Bad to the Bone: The Effects of Therapeutic Glucocorticoids on Osteoblasts and Osteocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.835720
Abstract: Despite the continued development of specialized immunosuppressive therapies in the form of monoclonal antibodies, glucocorticoids remain a mainstay in the treatment of rheumatological and auto-inflammatory disorders. Therapeutic glucocorticoids are unmatched in the breadth of their… read more here.
Keywords: bad bone; therapeutic glucocorticoids; cells osteoblast; osteoblast lineage ... See more keywords
Impact of the host response and osteoblast lineage cells on periodontal disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.998244
Abstract: Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell RNA-seq experiments have provided new insight into how resident cells and infiltrating immune cells function in response to bacterial challenge in periodontal… read more here.
Keywords: bone; osteoblast lineage; formation; response ... See more keywords
Role of K+ and Ca2+-Permeable Channels in Osteoblast Functions
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910459
Abstract: Bone-forming cells or osteoblasts play an important role in bone modeling and remodeling processes. Osteoblast differentiation or osteoblastogenesis is orchestrated by multiple intracellular signaling pathways (e.g., bone morphogenetic proteins (BMP) and Wnt signaling pathways) and… read more here.
Keywords: permeable channels; lineage cells; role; osteoblast lineage ... See more keywords