A Bone-Penetrating Precise Controllable Drug Release System Enables Localized Treatment of Osteoporotic Fracture Prevention via Modulating Osteoblast-Osteoclast Communication.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207195
Abstract: Improving local bone mineral density (BMD) at fracture-prone sites of bone is a clinical concern for osteoporotic fracture prevention. In this study, a featured radial extracorporeal shock wave (rESW) responsive nano-drug delivery system (NDDS) is… read more here.
Keywords: fracture; fracture prevention; bone; osteoclast communication ... See more keywords
Chemokine ligand 28 (CCL28) negatively regulates trabecular bone mass by suppressing osteoblast and osteoclast activities
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-021-01210-9
Abstract: Bone metabolism imbalances cause bone metabolism diseases, like osteoporosis, through aging. Although some chemokines are known to be involved in bone mass regulation, many have not been investigated. Thus, the present study aimed to investigate… read more here.
Keywords: bone; osteoblast osteoclast; bone mass; osteoclast activities ... See more keywords
Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.
Sign Up to like & getrecommendations! Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2017.08.013
Abstract: Bone tissue undergoes permanent and lifelong remodeling with a concerted action of bone-building osteoblasts and bone-resorbing osteoclasts. A precise cooperation between those two cell types is critical in the complex process of bone renewal. Galectin-3… read more here.
Keywords: bone homeostasis; galectin; bone; osteoblast osteoclast ... See more keywords
Dextromethorphan upregulates osteoblast and osteoclast activity but does not attenuate ovariectomy‐induced osteoporosis
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.01.011
Abstract: Aims: Study on the in vivo regulatory role of glutamate in osteoblast (OB) and osteoclast (OC) differentiation is less advanced. The present study investigated the effect of dextromethorphan (DXM), an N‐methyl‐D‐aspartate receptors (NMDARs) antagonist, on… read more here.
Keywords: bone; osteoblast osteoclast; upregulates osteoblast; dxm ... See more keywords
Epimedii Folium and Ligustri Lucidi Fructus Promote Osteoblastogenesis and Inhibit Osteoclastogenesis against Osteoporosis via Acting on Osteoblast-Osteoclast Communication
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/7212642
Abstract: Osteoblast (OB) and osteoclast (OC) play important roles in bone formation and bone resorption, which can communicate with each other through cytokine paracrine. Previous studies have confirmed that Epimedii Folium (EF) and Ligustri Lucidi Fructus… read more here.
Keywords: llf; communication; expression; osteoblast osteoclast ... See more keywords
The Effect of Palm Tocotrienol on Surface Osteoblast and Osteoclast in Excess Glucocorticoid Osteoporotic Rat Model
Sign Up to like & getrecommendations! Published in 2018 at "Sains Malaysiana"
DOI: 10.17576/jsm-2018-4711-16
Abstract: A balanced interaction between osteoblast and osteoclast plays a major role in maintaining bone strength and structural integrity. Tocotrienol, a palm derivative with potent antioxidant properties showed an anti-osteoporotic effect but little is known about… read more here.
Keywords: osteoblast osteoclast; palm tocotrienol; adrx dexa; tocotrienol ... See more keywords