Articles with "osteoblastic differentiation" as a keyword



The role of lysophosphatidylcholine acyltransferase 2 in osteoblastic differentiation of C2C12 cells

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Published in 2024 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13845

Abstract: Glycerophospholipids, a primary component of cellular membranes, play important structural and functional roles in cells. In the remodelling pathway (Lands' cycle), the concerted actions of phospholipase As and lysophospholipid acyltransferases (LPLATs) contribute to the incorporation… read more here.

Keywords: osteoblastic differentiation; c2c12 cells; lysophosphatidylcholine acyltransferase; differentiation c2c12 ... See more keywords

Mineralized nanofibrous scaffold promotes phenamil‐induced osteoblastic differentiation while mitigating adipogenic differentiation

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Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.3007

Abstract: Large bone defects represent a significant unmet medical challenge. Cost effectiveness and better stability make small molecule organic compounds a more promising alternative compared with biomacromolecules, for example, growth factors/hormones, in regenerative medicine. However, one… read more here.

Keywords: medicine; osteoblastic differentiation; phenamil induced; bone ... See more keywords

CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway

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Published in 2024 at "Medical Oncology"

DOI: 10.1007/s12032-024-02301-z

Abstract: Inflammation disrupts bone metabolism and leads to bone damage. C-reactive protein (CRP) is a typical inflammation marker. Although CRP measurement has been conducted for many decades, how osteoblastic differentiation influences molecular mechanisms remains largely unknown.… read more here.

Keywords: differentiation; primary cilia; osteoblastic differentiation; crp ... See more keywords

Capacity of octacalcium phosphate to promote osteoblastic differentiation toward osteocytes in vitro.

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Published in 2018 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2018.01.026

Abstract: Octacalcium phosphate (OCP) has been shown to act as a nucleus for initial bone deposition and enhancing the early stages of osteoblastic differentiation. However, the effect on differentiation at the late stage into osteocytes has… read more here.

Keywords: capacity; osteoblastic differentiation; phosphate; differentiation ... See more keywords

Mineral trioxide aggregate immersed in sodium hypochlorite reduce the osteoblastic differentiation of human periodontal ligament stem cells

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-01545-3

Abstract: White mineral trioxide aggregate (WMTA) is a root canal treatment material, which is known to exhibit a dark brown color when in contact with sodium hypochlorite solution (NaOCl). This study aimed to investigate the effects… read more here.

Keywords: mineral trioxide; osteoblastic differentiation; wmta; trioxide aggregate ... See more keywords

The importance of cellular and exosomal miRNAs in mesenchymal stem cell osteoblastic differentiation

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-85306-2

Abstract: The differentiation of osteoblasts is under complex regulation that includes autocrine and paracrine signaling from MSCs. Exosomes are important components of the MSC secretome and their cargo contains numerous miRNAs. In this study, the importance… read more here.

Keywords: hmscs; importance; osteoblastic differentiation; hmsc exosomes ... See more keywords

Pentraxin 3 promotes the osteoblastic differentiation of MC3T3-E1 cells through the PI3K/Akt signaling pathway

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Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20201165

Abstract: Abstract Osteoblast cells are responsible for synthesizing new bone tissue, and determining how to control osteoblastic differentiation is vital to the treatment of osteoporosis. In the present study, we show that pentraxin 3 (PTX3) signaling… read more here.

Keywords: differentiation; differentiation mc3t3; ptx3; osteoblastic differentiation ... See more keywords

Trelagliptin stimulates osteoblastic differentiation by increasing runt-related transcription factor 2 (RUNX2): a therapeutic implication in osteoporosis

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Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1900633

Abstract: ABSTRACT Osteoporosis, an aging-associated bone metabolic disease, is affecting millions of people worldwide. The deregulated process of osteoblastic differentiation has been linked with the progression of osteoporosis. Trelagliptin is a long-acting inhibitor of DPP-4 used… read more here.

Keywords: osteoblastic differentiation; differentiation; osteoporosis trelagliptin; trelagliptin stimulates ... See more keywords

Effect of the combined use of enamel matrix derivative and atelocollagen sponge scaffold on osteoblastic differentiation of mouse induced pluripotent stem cells in vitro

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Published in 2018 at "Journal of Periodontal Research"

DOI: 10.1111/jre.12511

Abstract: BACKGROUND AND OBJECTIVE Induced pluripotent stem cells (iPSCs) are a candidate cell source in periodontal regenerative therapy. Enamel matrix derivative (EMD) has been shown to regenerate periodontal tissues, and atelocollagen sponge (ACS) is considered a… read more here.

Keywords: microscopy; acs; osteoblastic differentiation; group ... See more keywords

Gingival fibroblasts prevent BMP‐mediated osteoblastic differentiation

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Published in 2019 at "Journal of Periodontal Research"

DOI: 10.1111/jre.12631

Abstract: Objectives The inhibitory action of the superficial gingival connective tissues may limit the regenerative potential of alveolar bone in periodontal therapy or dental implant applications. The aims of this study were to investigate the hypothesis… read more here.

Keywords: expression; osteoblastic differentiation; activity; gingival fibroblasts ... See more keywords
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Imaging characteristics of metaplastic breast cancer with osteoblastic differentiation

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Published in 2020 at "BMJ Case Reports"

DOI: 10.1136/bcr-2020-235050

Abstract: An 82-year-old female presented to her breast surgeon with a hard, painful mass in the left breast. Mammography demonstrated a new hyperdense mass with pleomorphic calcifications of trabeculated appearance. Ultrasound-guided biopsy demonstrated a hypoechoic mass… read more here.

Keywords: breast; osteoblastic differentiation; metaplastic breast; characteristics metaplastic ... See more keywords