Cell trafficking and regulation of osteoblastogenesis by extracellular vesicle associated bone morphogenetic protein 2.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12155
Abstract: Extracellular vesicles (EVs) are characterized by complex cargo composition and carry a wide array of signalling cargo, including growth factors (GFs). Beyond surface-associated GFs, it is unclear if EV intralumenal growth factors are biologically active.… read more here.
Keywords: cell trafficking; bmp2; evs; osteoblastogenesis ... See more keywords
Dehydrodiconiferyl alcohol promotes BMP-2-induced osteoblastogenesis through its agonistic effects on estrogen receptor.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.079
Abstract: Estrogen deficiency results in an imbalance between the levels of bone-resorping osteoclasts and bone-forming osteoblasts, eventually leading to overall bone loss. Dehydrodiconiferyl alcohol (DHCA), a lignan compound originally isolated from Cucurbita moschata, has been shown… read more here.
Keywords: dhca; induced osteoblastogenesis; bmp induced; osteoblastogenesis ... See more keywords
Hedgehog Activation Regulates Human Osteoblastogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2020.05.008
Abstract: Summary Two genetic diseases, Gorlin syndrome and McCune-Albright syndrome (MAS), show completely opposite symptoms in terms of bone mineral density and hedgehog (Hh) activity. In this study, we utilized human induced pluripotent stem cell (iPSC)-based… read more here.
Keywords: regulates human; hedgehog activation; activation regulates; hedgehog ... See more keywords
Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17416
Abstract: Bone remodelling is mediated by orchestrated communication between osteoclasts and osteoblasts which, in part, is regulated by coupling and anti-coupling factors. Amongst formally known anti-coupling factors, Semaphorin 4D (Sema4D), produced by osteoclasts, plays a key… read more here.
Keywords: tace mab; tace; osteoclast precursors; anti tace ... See more keywords
Epimedii Folium and Ligustri Lucidi Fructus Promote Osteoblastogenesis and Inhibit Osteoclastogenesis against Osteoporosis via Acting on Osteoblast-Osteoclast Communication
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/7212642
Abstract: Osteoblast (OB) and osteoclast (OC) play important roles in bone formation and bone resorption, which can communicate with each other through cytokine paracrine. Previous studies have confirmed that Epimedii Folium (EF) and Ligustri Lucidi Fructus… read more here.
Keywords: llf; communication; expression; osteoblast osteoclast ... See more keywords
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221116879
Abstract: Morroniside is known to improve osteoporosis by promoting osteoblastogenesis. The activation of PI3K/Akt/mTOR signaling is a significant mechanism in morroniside-promoted osteoblastogenesis. It is well known that protective autophagy is an important factor in osteoblastogenesis. However,… read more here.
Keywords: beclin1; osteoblastogenesis; mtor; autophagy ... See more keywords
Osteoprotective Roles of Green Tea Catechins
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9111136
Abstract: Osteoporosis is the second most common disease only secondary to cardiovascular disease, with the risk of fracture increasing with age. Osteoporosis is caused by an imbalance between osteoblastogenesis and osteoclastogenesis processes. Osteoclastogenesis may be enhanced,… read more here.
Keywords: green tea; tea catechins; osteoprotective roles; tea ... See more keywords