Multileveled Hierarchical Hydrogel with Continuous Biophysical and Biochemical Gradients for Enhanced Repair of Full‐Thickness Osteochondral Defect
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202209565
Abstract: The repair of hierarchical osteochondral defect requires sophisticated gradient reestablishment; however, few strategies for continuous gradient casting consider the relevance to clinical practice regarding cell adaptability, multiple gradient elements, and precise gradient mirroring native tissue.… read more here.
Keywords: hydrogel; biophysical biochemical; biochemical gradients; hydrogel continuous ... See more keywords
Replacement of osteochondral defect of large joints: An experimental model in sheep.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of orthopaedics"
DOI: 10.1016/j.jor.2019.03.001
Abstract: Aim To improve the treatment results of patients with osteochondral defects of large joints. Materials and methods A prospective study was conducted on 30 animals (60 knee joints) aged 1.5-3 years. All animals were divided… read more here.
Keywords: osteochondral defect; joints experimental; experimental model; replacement osteochondral ... See more keywords
Improvement of Cartilage Repair With Biologically Regulated Marrow Stimulation by Blocking TGF-β1 in A Rabbit Osteochondral Defect Model
Sign Up to like & getrecommendations! Published in 2019 at "Orthopaedic Journal of Sports Medicine"
DOI: 10.1177/2325967119s00263
Abstract: Objectives: Application of growth factors for cartilage injury has been considered in recent studies; however, the effect of blocking detrimental growth factors for cartilage injury has not been well described. It is known that transforming… read more here.
Keywords: bms; cartilage repair; blocking tgf; group ... See more keywords
Large osteochondral defect in the lateral femoral condyle reconstructed by Atelocollagen-associated autologous chondrocyte implantation combined with anterior cruciate ligament reconstruction
Sign Up to like & getrecommendations! Published in 2020 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-020-03531-8
Abstract: Background Articular surface damage commonly associated with rupture of the anterior cruciate ligament (ACL). Large osteochondral defect, which consists of a severe depression fracture and a large cartilage defect, need to be treated due to… read more here.
Keywords: reconstruction; femoral condyle; osteochondral defect; anterior cruciate ... See more keywords
Functional Characterization of Ovine Dorsal Root Ganglion Neurons Reveal Peripheral Sensitization after Osteochondral Defect
Sign Up to like & getrecommendations! Published in 2021 at "eNeuro"
DOI: 10.1523/eneuro.0237-21.2021
Abstract: Abstract Knee joint trauma can cause an osteochondral defect (OD), a risk factor for osteoarthritis (OA) and cause of debilitating pain in patients. Rodent OD models are less translatable because of their smaller joint size… read more here.
Keywords: dorsal root; pain; osteochondral defect; drg neurons ... See more keywords
Heat-Treated Osteochondral Allograft and Autologous Chondrocyte Implantation for a Large Osteochondral Defect
Sign Up to like & getrecommendations! Published in 2022 at "JBJS Case Connector"
DOI: 10.2106/jbjs.cc.22.00171
Abstract: Case: A 21-year-old man presented with knee pain secondary to tibial plateau malunion and an osteochondral defect 1 year after open reduction and initial fixation. Two-stage reconstruction with transplantation of a bulk heat-treated osteochondral allograft… read more here.
Keywords: autologous chondrocyte; heat treated; osteochondral allograft; allograft autologous ... See more keywords