Ultrashort echo time magnetic resonance imaging of the osteochondral junction
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4843
Abstract: Osteoarthritis is a common chronic degenerative disease that causes pain and disability with increasing incidence worldwide. The osteochondral junction is a dynamic region of the joint that is associated with the early development and progression… read more here.
Keywords: echo time; osteochondral junction; junction; time magnetic ... See more keywords
Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: a pilot study.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.02.020
Abstract: This study investigates the influence of osteoarthritis (OA) disease severity on the bio-composition of the osteochondral junction at the human tibial plateau using Raman microspectroscopy. We specifically aim to analyze the spatial composition of mineralized… read more here.
Keywords: study; osteochondral junction; tissue specific; composition ... See more keywords
Subchondral bone plate thickness is associated with micromechanical and microstructural changes in the bovine patella osteochondral junction with different levels of cartilage degeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2022.105158
Abstract: The influence of joint degeneration on the biomechanical properties of calcified cartilage and subchondral bone plate at the osteochondral junction is relatively unknown. Common experimental difficulties include accessibility to and visualization of the osteochondral junction,… read more here.
Keywords: bone; degeneration; subchondral bone; osteochondral junction ... See more keywords
Gremlin-1 and BMP-4 Overexpressed in Osteoarthritis Drive an Osteochondral-Remodeling Program in Osteoblasts and Hypertrophic Chondrocytes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042084
Abstract: Osteoarthritis (OA) is a whole joint disease characterized by an important remodeling of the osteochondral junction. It includes cartilage mineralization due to chondrocyte hypertrophic differentiation and bone sclerosis. Here, we investigated whether gremlin-1 (Grem-1) and… read more here.
Keywords: osteochondral junction; bmp; hypertrophic chondrocytes; grem bmp ... See more keywords