Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.09.003
Abstract: Silk fibroin (SF) is considered biocompatible and biodegradable for osteochondral repair. However, it lacks a bioactive domain for cell adhesion, proliferation and differentiation, limiting its therapeutic efficacy. To revamp SF as a biomimicking and bioactive… read more here.
Keywords: osteochondral repair; scaffold; dht; silk ... See more keywords
Selective laser sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.05.021
Abstract: Osteochondral defects cannot be adequately self-repaired due to the presence of the sophisticated hierarchical structure and the lack of blood supply in cartilage. Thus, one of the major challenges remaining in this field is the… read more here.
Keywords: gradient composition; selective laser; osteochondral repair; architecture gradient ... See more keywords
Honeycomb-like biomimetic scaffold by functionalized antibacterial hydrogel and biodegradable porous Mg alloy for osteochondral regeneration
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1417742
Abstract: Introduction: Osteochondral repair poses a significant challenge due to its unique pathological mechanisms and complex repair processes, particularly in bacterial tissue conditions resulting from open injuries, infections, and surgical contamination. This study introduces a biomimetic… read more here.
Keywords: magnesium; analysis; scaffold; repair ... See more keywords
Manufacture of Bilayered Composite Hydrogels with Strong, Elastic, and Tough Properties for Osteochondral Repair Applications
Sign Up to like & getrecommendations! Published in 2023 at "Biomimetics"
DOI: 10.3390/biomimetics8020203
Abstract: Layered composite hydrogels have been considered attractive materials for use in osteochondral repair and regeneration. These hydrogel materials should be mechanically strong, elastic, and tough besides fulfilling some basic requirements such as biocompatibility and biodegradability.… read more here.
Keywords: bilayered composite; composite hydrogels; elastic tough; strong elastic ... See more keywords
Exosomal Interventions in Bone and Osteochondral Repair: Mechanisms and Outcomes
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262211172
Abstract: Critically sized bone defects remain a global health and economic burden, and biomaterials associated with stem cell therapy have been widely applied as a significant strategy for bone regeneration. Due to limitations related to cell… read more here.
Keywords: interventions bone; repair mechanisms; bone osteochondral; exosomal interventions ... See more keywords
Silk fibroin-based biomaterials for cartilage/osteochondral repair
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.74548
Abstract: Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not only causes great physiological and psychological harm to patients, but also puts great pressure on the social healthcare system.… read more here.
Keywords: silk fibroin; based biomaterials; biomaterials cartilage; cartilage osteochondral ... See more keywords