Enzyme-crosslinked gene-activated matrix for the induction of mesenchymal stem cells in osteochondral tissue regeneration.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.09.008
Abstract: The development of osteochondral tissue engineering is an important issue for the treatment of traumatic injury or aging associated joint disease. However, the different compositions and mechanical properties of cartilage and subchondral bone show the… read more here.
Keywords: osteochondral tissue; regeneration; tissue; gene activated ... See more keywords
Functionally graded multilayer scaffolds for in vivo osteochondral tissue engineering.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.07.039
Abstract: Osteochondral tissue repair remains a significant challenge in orthopedic surgery. Tissue engineering of osteochondral tissue has transpired as a potential therapeutic solution as it can effectively regenerate bone, cartilage, and the bone-cartilage interface. While advancements… read more here.
Keywords: osteochondral tissue; tissue engineering; layer; tissue ... See more keywords
Engineering of gradient osteochondral tissue: From nature to lab.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.01.071
Abstract: The osteochondral tissue is an interface between two distinct tissues: articular cartilage and bone. These two tissues are significantly diverse with regard to their chemical compositions, mechanical properties, structure, electrical properties, and the amount of… read more here.
Keywords: osteochondral tissue; gradient osteochondral; engineering gradient; tissue ... See more keywords
Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.05.011
Abstract: In spite of the considerable achievements in the field of regenerative medicine in the past several decades, osteochondral defect regeneration remains a challenging issue among diseases in the musculoskeletal system because of the spatial complexity… read more here.
Keywords: osteochondral tissue; articular cartilage; tissue engineering; tissue ... See more keywords
Facile green synthesis of bioresorbable polyester from soybean oil and recycled plastic waste for osteochondral tissue regeneration
Sign Up to like & getrecommendations! Published in 2020 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2019.109338
Abstract: Abstract Despite the recent progress in the field of tissue engineering still there are great challenges to regenerate osteochondral tissue interface due to its complex material composition and mechanical properties. A series of biomaterials have… read more here.
Keywords: osteochondral tissue; waste; oil recycled; tissue ... See more keywords
Preparation of Assemblable Chondral and Subchondral Bone Microtissues for Osteochondral Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c00997
Abstract: Microtissues exhibit great advantages in injecting with minimum invasiveness, mimicking natural tissues, and promoting tissue regeneration. However, very few studies have focused on the construction of osteochondral microtissues that could simultaneously support hyaline-like cartilage and… read more here.
Keywords: bone microtissues; bone; microtissues could; osteochondral tissue ... See more keywords
A triphasic biomimetic BMSC-loaded scaffold for osteochondral integrated regeneration in rabbits and pigs.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm02148j
Abstract: Osteochondral tissue involves cartilage, calcified cartilage and subchondral bone. These tissues differ significantly in chemical compositions, structures, mechanical properties and cellular compositions. Therefore, the repairing materials face different osteochondral tissue regeneration needs and rates. In… read more here.
Keywords: regeneration; bone; calcified cartilage; cartilage ... See more keywords
3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs.
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac61a3
Abstract: Recently developed modular bioassembly techniques hold tremendous potential in tissue engineering and regenerative medicine, due to their ability to recreate the complex microarchitecture of native tissue. Here, we developed a novel approach to fabricate hybrid… read more here.
Keywords: cell instructive; tissue; chondrogenic osteogenic; instructive chondrogenic ... See more keywords
Human gelatin-based composite hydrogels for osteochondral tissue engineering and their adaptation into bioinks for extrusion, inkjet, and digital light processing bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac8768
Abstract: The investigation of novel hydrogel systems allows for the study of relationships between biomaterials, cells, and other factors within osteochondral tissue engineering. Three-dimensional (3D) printing is a popular research method that can allow for further… read more here.
Keywords: light processing; extrusion inkjet; tissue engineering; osteochondral tissue ... See more keywords
Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00411
Abstract: Osteoarthritis (OA) is a chronic disease mainly characterized by degenerative changes in cartilage, but other joint elements such as bone are also affected. To date, there are no disease-modifying OA drugs (DMOADs), owing in part… read more here.
Keywords: osteochondral tissue; chip derived; tissue chip; derived ipscs ... See more keywords
Piezoelectric Electrospun Fibrous Scaffolds for Bone, Articular Cartilage and Osteochondral Tissue Engineering
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23062907
Abstract: Osteochondral tissue (OCT) related diseases, particularly osteoarthritis, number among the most prevalent in the adult population worldwide. However, no satisfactory clinical treatments have been developed to date to resolve this unmet medical issue. Osteochondral tissue… read more here.
Keywords: piezoelectric electrospun; tissue engineering; osteochondral tissue; articular cartilage ... See more keywords