The W9 peptide inhibits osteoclastogenesis and osteoclast activity by downregulating osteoclast autophagy and promoting osteoclast apoptosis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular histology"
DOI: 10.1007/s10735-021-10030-0
Abstract: The W9 peptide has been shown to act as a receptor activator for nuclear factor-κB ligand (RANKL) antagonist and tumor necrosis factor (TNF)-α antagonist, which can promote bone formation and inhibit bone resorption. Studies on… read more here.
Keywords: peptide; apoptosis; osteoclastogenesis osteoclast; osteoclast autophagy ... See more keywords
HDL impairs osteoclastogenesis and induces osteoclast apoptosis via upregulation of ABCG1 expression
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DOI: 10.1093/abbs/gmy081
Abstract: Cholesterol is one of the major components of biological membranes and has an important function in osteoclast formation and survival. It has been reported that high-density lipoprotein (HDL) promotes cholesterol efflux from osteoclasts and induces… read more here.
Keywords: cholesterol efflux; abcg1 expression; osteoclast apoptosis; hdl ... See more keywords
Cigarette Smoke Exposure Inhibits Osteoclast Apoptosis via the mtROS Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Dental Research"
DOI: 10.1177/00220345211009471
Abstract: It is widely known that smoking is a risk factor for bone loss and plays a key role in osteopenia. Despite this well-known association, the mechanisms by which smoking affects bone have not been definitively… read more here.
Keywords: bone; cigarette smoke; osteoclast apoptosis;