PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz028
Abstract: Abstract PIP5k1β is crucial to the generation of phosphotidylinosotol (4, 5)P2. PIP5k1β participates in numerous cellular activities, such as B cell and platelet activation, cell phagocytosis and endocytosis, cell apoptosis, and cytoskeletal organization. In the… read more here.
Keywords: osteoclast osteoblast; bone homeostasis; pip5k1; differentiation ... See more keywords
Overexpression of Neurogenin 1 Negatively Regulates Osteoclast and Osteoblast Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126708
Abstract: Neurogenin 1 (Ngn1) belongs to the basic helix–loop–helix (bHLH) transcription factor family and plays important roles in specifying neuronal differentiation. The present study aimed to determine whether forced Ngn1 expression contributes to bone homeostasis. Ngn1… read more here.
Keywords: overexpression neurogenin; factor; differentiation; osteoblast differentiation ... See more keywords