Asiatic Acid Attenuates Bone Loss by Regulating Osteoclastic Differentiation
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DOI: 10.1007/s00223-019-00596-z
Abstract: Anti-resorptive agents like bisphosphonates have been widely used for the treatment of postmenopausal osteoporosis. However, their long-term safety and efficacy are still controversial. This study is to examine the effect of Asiatic acid (AA) in… read more here.
Keywords: osteoclastic differentiation; differentiation; bone loss; asiatic acid ... See more keywords
Morinda officinalis polysaccharide enable suppression of osteoclastic differentiation by exosomes derived from rat mesenchymal stem cells
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DOI: 10.1080/13880209.2022.2093385
Abstract: Abstract Context Morinda officinalis F.C. How. (MO) (Rubiaceae) can strengthen bone function. Objective To examine the functional mechanism and effect of MO polysaccharides (MOPs) in rats with glucocorticoid-induced osteoporosis (GIOP). Materials and methods Rats with… read more here.
Keywords: osteoclastic differentiation; bone; mesenchymal stem; morinda officinalis ... See more keywords
Periplaneta Americana extract inhibits osteoclastic differentiation in vitro
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DOI: 10.1111/cpr.13341
Abstract: Periplaneta americana extract (PAE) is proven to be promising in treating fever, wound healing, liver fibrosis, and cardiovascular disease. However, the role of PAE in skeletal disorders remains unclear. This study investigated whether PAE regulates… read more here.
Keywords: osteoclastic differentiation; americana extract; differentiation vitro; periplaneta americana ... See more keywords
Endothelial Progenitor Cells Enhance the Migration and Osteoclastic Differentiation of Bone Marrow-Derived Macrophages in vitro and in a Mouse Femur Fracture Model through Talin-1
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DOI: 10.1159/000492993
Abstract: Background/Aims: Bone resorption mediated by osteoclasts plays an important role in bone healing. Endothelial progenitor cells (EPCs) promote bone repair by stimulating neovascularization and osteogenesis. However, the role of EPCs in osteoclast formation and function… read more here.
Keywords: fracture model; bone; differentiation; osteoclastic differentiation ... See more keywords
Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts
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DOI: 10.3390/ijms19061742
Abstract: The present study evaluated the protective effects of melatonin in ethanol (EtOH)-induced senescence and osteoclastic differentiation in human periodontal ligament cells (HPDLCs) and cementoblasts and the underlying mechanism. EtOH increased senescence activity, levels of reactive… read more here.
Keywords: etoh induced; senescence; senescence osteoclastic; differentiation ... See more keywords