Apoptotic extracellular vesicles alleviate Pg-LPS induced inflammation of macrophages via AMPK/SIRT1/NF-κB pathway and inhibit adjacent osteoclasts formation.
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DOI: 10.1002/jper.21-0657
Abstract: BACKGROUND Periodontitis is caused by the imbalance of anti-bacteria immune response and excessive inflammation whereas macrophages play an important role in inflammation. Thus, it is critical for finding efficient anti-inflammatory strategies to alleviate periodontal inflammation… read more here.
Keywords: inflammation; sirt1 pathway; ampk sirt1; osteoclasts formation ... See more keywords