Quantitative Evaluation of Osteocyte Morphology and Bone Anisotropic Extracellular Matrix in Rat Femur
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DOI: 10.1007/s00223-021-00852-1
Abstract: Osteocytes are believed to play a crucial role in mechanosensation and mechanotransduction which are important for maintenance of mechanical integrity of bone. Recent investigations have revealed that the preferential orientation of bone extracellular matrix (ECM)… read more here.
Keywords: orientation; extracellular matrix; bone; rat femur ... See more keywords
Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality
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DOI: 10.1007/s11914-019-00508-y
Abstract: Purpose of ReviewThis article provides a review on the variability of the osteocyte lacunar network in the human skeleton. It highlights characteristics of the osteocyte lacunar network in relation to different skeletal sites and fracture… read more here.
Keywords: lacunar network; osteocyte; osteocyte lacunar; variability ... See more keywords
Effect of osteoporosis treatment agents on the cortical bone osteocyte microenvironment in adult estrogen-deficient, osteopenic rats
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DOI: 10.1016/j.bonr.2018.02.005
Abstract: Though osteoporosis is a significant cause of disability worldwide, treatment with pharmacologic agents decreases risk of fragility fracture. Though these treatments act through the bone remodeling system to improve bone mass, it is unclear if… read more here.
Keywords: treatment; matrix; bone; osteoporosis treatment ... See more keywords
Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin
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DOI: 10.3390/ijms24054718
Abstract: Calcium/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) regulates bone remodeling through its effects on osteoblasts and osteoclasts. However, its role in osteocytes, the most abundant bone cell type and the master regulator of bone remodeling,… read more here.
Keywords: camkk2; bone; osteocyte; camkk2 regulates ... See more keywords