Gelatin Nanoparticle-Injectable Platelet-Rich Fibrin Double Network Hydrogels with Local Adaptability and Bioactivity for Enhanced Osteogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901469
Abstract: Bone healing is a dynamic process regulated by biochemical signals such as chemokines and growth factors, and biophysical signals such as topographical and mechanical features of extracellular matrix or mechanical stimuli. Hereby, a mechanically tough… read more here.
Keywords: network; platelet rich; rich fibrin; injectable platelet ... See more keywords
The Synergy of Topographical Micropatterning and Ta|TaCu Bilayered Thin Film on Titanium Implants Enables Dual-Functions of Enhanced Osteogenesis and Anti-Infection.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202002020
Abstract: Poor osteogenesis and implant-associated infection are the two leading causes of failure for dental and orthopedic implants. Surface design with enhanced osteogenesis often fails in antibacterial activity, or vice versa. Herein, a surface design strategy,… read more here.
Keywords: surface; thin film; enhanced osteogenesis; titanium ... See more keywords
Biomimetic Metal−Organic Frameworks as Targeted Vehicles to Enhance Osteogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102821
Abstract: Although engineered nanoparticles loaded with specific growth factors are used to regulate differentiation of stem cells, the low loading efficiency and biocompatibility are still great challenges in tissue repair. A nature‐inspired biomimetic delivery system with… read more here.
Keywords: zif scm; dex zif; osteogenesis; scm ... See more keywords
A comparison of human mesenchymal stem cell osteogenesis in poly(ethylene glycol) hydrogels as a function of MMP‐sensitive crosslinker and crosslink density in chemically defined medium
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26957
Abstract: This study investigated osteogenesis of human mesenchymal stem cells encapsulated in matrix‐metalloproteinase (MMP)‐sensitive poly(ethylene glycol) (PEG) hydrogels in chemically defined medium (10 ng/ml bone morphogenic factor‐2). Thiol‐norbornene photoclick hydrogels were formed with CRGDS and crosslinkers of… read more here.
Keywords: defined medium; mmp sensitive; osteogenesis; cell ... See more keywords
Neurexin Superfamily Cell Membrane Receptor Contactin‐Associated Protein Like‐4 (Cntnap4) Is Involved in Neural EGFL‐Like 1 (Nell‐1)‐Responsive Osteogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3524
Abstract: Contactin‐associated protein‐like 4 (Cntnap4) is a member of the neurexin superfamily of transmembrane molecules that have critical functions in neuronal cell communication. Cntnap4 knockout mice display decreased presynaptic gamma‐aminobutyric acid (GABA) and increased dopamine release… read more here.
Keywords: cntnap4; nell cntnap4; nell responsive; receptor ... See more keywords
Antagonism Between PEDF and TGF‐β Contributes to Type VI Osteogenesis Imperfecta Bone and Vascular Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4540
Abstract: Osteogenesis imperfecta (OI) is a heterogeneous genetic disorder of bone and connective tissue, also known as brittle bone disease. Null mutations in SERPINF1, which encodes pigment epithelium‐derived factor (PEDF), cause severe type VI OI, characterized… read more here.
Keywords: pedf; bone; osteogenesis; type ... See more keywords
Parathyroid hormone‐related peptide (1–34) promotes tooth eruption and inhibits osteogenesis of dental follicle cells during tooth development
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27857
Abstract: Dental follicle cells (DFCs) activate and recruit osteoclasts for tooth development and tooth eruption, whereas DFCs themselves differentiate into osteoblasts to form alveolar bone surrounding tooth roots through the interaction with Hertwig's epithelial root sheath… read more here.
Keywords: eruption; tooth eruption; dfcs; tooth development ... See more keywords
Static osteogenesis does not precede dynamic osteogenesis in periosteal ossification of Pleurodeles (Caudata, Amphibia) and Pogona (Squamata, Lepidosauria)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Morphology"
DOI: 10.1002/jmor.20659
Abstract: Two successive mechanisms have been described in perichondral ossification: (1) in static osteogenesis, mesenchymal cells differentiate into stationary osteoblasts oriented randomly, which differentiate into osteocytes in the same site; (2) in dynamic osteogenesis, mesenchymal cells… read more here.
Keywords: dynamic osteogenesis; caudata amphibia; static osteogenesis; ossification ... See more keywords
Total flavonoids of Rhizoma drynariae promote angiogenesis and osteogenesis in bone defects
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DOI: 10.1002/ptr.7525
Abstract: Bone defects are difficult to heal, which conveys a heavy burden to patients' lives and their economy. The total flavonoids of Rhizoma drynariae (TFRD) can promote the osteogenesis of distraction osteogenesis. However, the dose effect… read more here.
Keywords: flavonoids rhizoma; bone; rhizoma drynariae; osteogenesis ... See more keywords
Regulation of Macrophage Polarization Through Periodic Photo-Thermal Treatment to Facilitate Osteogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202691
Abstract: The richened reactive oxygen species (ROS) and their derived excessive inflammation at bone injured sites hinder osteogenesis of endosseous Ti-based implants. Herein, anti-oxidized polydopamine (PDA) is deposited on hydrothermal growth formed hydroxyapatite (HA) nanorods on… read more here.
Keywords: periodic photo; thermal treatment; photo thermal; osteogenesis ... See more keywords
LncRNA, PLXDC2‐OT promoted the osteogenesis potentials of MSCs by inhibiting the deacetylation function of RBM6/SIRT7 complex and OSX specific isoform
Sign Up to like & getrecommendations! Published in 2021 at "STEM CELLS"
DOI: 10.1002/stem.3362
Abstract: Bone regeneration and remodeling are complex physiological processes that are regulated by key transcription factors. Understanding the regulatory mechanism of key transcription factors on the osteogenic differentiation of mesenchymal stem cells (MSCs) is a key… read more here.
Keywords: osx; sirt7; function; osteogenesis ... See more keywords