Angiogenic and osteogenic effects of flavonoids in bone regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28162
Abstract: Bone is a highly vascularized tissue that relies on a close spatial and temporal interaction between blood vessels and bone cells. As a result, angiogenesis is critical for bone formation and healing. The vascular system… read more here.
Keywords: angiogenic osteogenic; bone; osteogenic effects; bone regeneration ... See more keywords
8-prenylgenistein exerts osteogenic effects via ER α and Wnt-dependent signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112186
Abstract: 8-prenylgenistein (8PG) was previously reported to exert stronger osteogenic activity than genistein, a well-known soy phytoestrogen. However, the molecular mechanism underlying the actions of 8PG on osteoblasts was far from clear. In the present study,… read more here.
Keywords: 8pg genistein; mc3t3 cells; signaling pathway; pathway ... See more keywords
Mitochondria-Targeted Cassic Acid Base Nanoprodrug for Enhanced Anti-Inflammatory and Osteogenic Effects in Osteoarthritis
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c03216
Abstract: CATPCS prodrug-based nanodrug delivery system (PNDDS), a mitochondria-targeted nanoprodrug combining Cassic acid (CA) with a PEG-modified chitosan-tripolyphosphate (TPP) molecule (CATPCS), overcomes the limitations of free Cassic acid in treating osteoarthritis (OA) and bone regeneration. FTIR… read more here.
Keywords: osteogenic effects; mitochondria targeted; catpcs; cassic acid ... See more keywords
Investigation of the osteogenic effects of ICA and ICSII on rat bone marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-86501-1
Abstract: Icariin (ICA) serves as the primary biologically active compound in traditional Chinese medicine Epimedium, while Icariside II (ICSII) represents one of its gastrointestinal metabolites. Although ICA and ICSII have demonstrated osteogenic differentiation- promoting effects on… read more here.
Keywords: differentiation; osteogenic effects; investigation osteogenic; expression ... See more keywords
LAPONITE® nano-silicates potentiate the angiogenic effects of FG-4592 and osteogenic effects of BMP-2.
Sign Up to like & getrecommendations! Published in 2024 at "Biomaterials science"
DOI: 10.1039/d4bm00636d
Abstract: LAPONITE®-based drug delivery systems offer many advantages due to the unique ionic and physical properties of LAPONITE®. The high ionicity and large surface area of LAPONITE® nanoparticles enable the intercalation and dissolution of biomolecules. In… read more here.
Keywords: effects bmp; osteogenic effects; laponite nano; silicates potentiate ... See more keywords
Analysis of the Osteogenic Effects of Biomaterials Using Numerical Simulation
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/6981586
Abstract: We describe the development of an optimization algorithm for determining the effects of different properties of implanted biomaterials on bone growth, based on the finite element method and bone self-optimization theory. The rate of osteogenesis… read more here.
Keywords: effects biomaterials; implanted biomaterials; analysis osteogenic; bone ... See more keywords
Multifunctional Mesoporous Silica Nanoparticles Reinforced Silk Fibroin Composite with Antibacterial and Osteogenic Effects for Infectious Bone Rehabilitation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s387347
Abstract: Background Existing implant materials cannot meet the essential multifunctional requirements of repairing infected bone defects, such as antibacterial and osteogenesis abilities. A promising strategy to develop a versatile biomimicry composite of the natural bone structure… read more here.
Keywords: mesoporous silica; bone; silk fibroin; osteogenic effects ... See more keywords
Antibacterial and pro-osteogenic effects of β-Defensin-2-loaded mesoporous bioglass.
Sign Up to like & getrecommendations! Published in 2020 at "Dental materials journal"
DOI: 10.4012/dmj.2020-105
Abstract: The human antimicrobial peptide beta-defensin-2 (hBD2) shows broad antibacterial activity and infrequent bacterial resistance. Here mesoporous bioactive glass (MBG) was loaded with hBD2, forming hBD2-loaded MBG (BD-MBG). The antibacterial and osteogenic effects of BD-MBG were… read more here.
Keywords: antibacterial pro; mbg; pro osteogenic; effects defensin ... See more keywords