Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells
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DOI: 10.1080/0886022x.2022.2072337
Abstract: Abstract Chronic kidney disease (CKD) has recently become a serious health and social concern. Vascular calcification, a common complication of CKD, is a risk factor that increases the incidence and mortality of cardiovascular events in… read more here.
Keywords: calcification; regulating osteogenic; ckd; vascular calcification ... See more keywords
Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions
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DOI: 10.3390/ijms21197207
Abstract: In diabetes mellitus, hyperglycemia promotes the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) to enhance medial vascular calcification, a common complication strongly associated with cardiovascular disease and mortality. The mechanisms involved are, however, still… read more here.
Keywords: sgk1; osteogenic transdifferentiation; calcification; high glucose ... See more keywords