A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300516
Abstract: The local application of drug-loaded bioactive scaffold materials is one of the important directions to solve the clinical problem of osteoporotic (OP) bone defects. This study retains the advantages of drug loading and mechanical properties… read more here.
Keywords: bone; related peptide; osteoporotic bone; parathyroid hormone ... See more keywords
PLGA Cage-like Structures Loaded with Sr/Mg-doped Hydroxyapatite for Repairing Osteoporotic Bone Defects.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200092
Abstract: Poly (lactic-co-glycolic acid) (PLGA)-based porous structures have a widespread application in bone defects. To solve its flaws in the bone application, hydroxyapatite (HA) is often introduced into PLGA-based systems, and ion doping endows HA with… read more here.
Keywords: plga cage; cage like; bone; repairing osteoporotic ... See more keywords
Biomechanics of Implant Fixation in Osteoporotic Bone
Sign Up to like & getrecommendations! Published in 2020 at "Current Osteoporosis Reports"
DOI: 10.1007/s11914-020-00614-2
Abstract: The purpose of this review is to critically evaluate the current literature regarding implant fixation in osteoporotic bone. Clinical studies have not only demonstrated the growing prevalence of osteoporosis in patients undergoing total joint replacement… read more here.
Keywords: osteoporotic bone; biomechanics; implant fixation; bone ... See more keywords
Longitudinal effects of low-intensity pulsed ultrasound on osteoporosis and osteoporotic bone defect in ovariectomized rats.
Sign Up to like & getrecommendations! Published in 2021 at "Ultrasonics"
DOI: 10.1016/j.ultras.2021.106360
Abstract: Low-intensity pulsed ultrasound (LIPUS) with an intensity (spatial average temporal average, ISATA) of 30Â mW/cm2 has been widely proved to be effective on impaired bone healing, but showing little effectiveness in the treatment of osteoporosis. We… read more here.
Keywords: osteoporotic bone; bone defect; intensity; lipus ... See more keywords
Chemical Self-Assembly of Multifunctional Hydroxyapatite with a Coral-like Nanostructure for Osteoporotic Bone Reconstruction.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b09879
Abstract: Bone defects/fractures are common in older people suffering from osteoporosis. Traditional hydroxyapatite (HA) materials for osteoporotic bone repair face many challenges, including limited bone formation and aseptic loosening of orthopedic implants. In this study, a… read more here.
Keywords: multifunctional hydroxyapatite; osteoporotic bone; self assembly; chemical self ... See more keywords
Biomechanical comparison of lag screw and non-spiral blade fixation of a novel femoral trochanteric nail in an osteoporotic bone model.
Sign Up to like & getrecommendations! Published in 2022 at "Scientific reports"
DOI: 10.1038/s41598-022-04844-5
Abstract: There is no consensus regarding the advantages of the lag screw type over the blade type for treating femoral trochanteric fractures. We aimed to investigate whether non-spiral blade (Conventional-Blade, Fid-Blade) nails provide better biomechanical fixation… read more here.
Keywords: lag screw; blade; osteoporotic bone; fixation ... See more keywords
Osteoporotic Bone: When and How to Use Augmentation?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Orthopaedic Trauma"
DOI: 10.1097/bot.0000000000001643
Abstract: The number of fragility fractures is rising, and treatment is a challenge for orthopaedic trauma surgeons. Various augmentation options have been developed to prevent mechanical failure. Different composites can be used based on the fracture… read more here.
Keywords: use augmentation; augmentation; bone use; osteoporotic bone ... See more keywords
Repair of Osteoporotic Bone Defects Using Adipose-Derived Stromal Cells and Umbilical Vein Endothelial Cells Seeded in Chitosan/Nanohydroxyapatite-P24 Nanocomposite Scaffolds
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nanomaterials"
DOI: 10.1155/2021/6237130
Abstract: Background. The cell regeneration and blood supply of bone defect lesions are restricted under osteoporotic pathological conditions, which make the healing of bone defect of osteoporosis still a great challenge. The current therapeutic strategies that… read more here.
Keywords: chitosan nanohydroxyapatite; osteoporotic bone; bone; nanocomposite scaffolds ... See more keywords
Evidence of a Causal Relationship between Serum Thyroid-Stimulating Hormone and Osteoporotic Bone Fractures
Sign Up to like & getrecommendations! Published in 2021 at "European Thyroid Journal"
DOI: 10.1159/000518058
Abstract: Objective: We aimed to validate the association of genome-wide association study (GWAS)-identified loci and polygenic risk score with serum thyroid-stimulating hormone (TSH) concentrations and the diagnosis of hypothyroidism. Then, the causal relationship between serum TSH… read more here.
Keywords: risk; osteoporotic bone; tsh; serum ... See more keywords
Analytic approach to explore dynamical osteoporotic bone turnover
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Difference Equations"
DOI: 10.1186/s13662-019-1986-7
Abstract: BackgroundThe dynamics of the osteoporotic bone turnover is studied in this paper with the aid of stability analysis of the associated mathematical model. Osteoporosis, which is a common bone disorder, is studied in this papper… read more here.
Keywords: analytic approach; bone turnover; bone; approach explore ... See more keywords
Melatonin Accelerates Osteoporotic Bone Defect Repair by Promoting Osteogenesis–Angiogenesis Coupling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.826660
Abstract: Previous studies have revealed that melatonin could play a role in anti-osteoporosis and promoting osteogenesis. However, the effects of melatonin treatment on osteoporotic bone defect and the mechanism underlying the effects of melatonin on angiogenesis… read more here.
Keywords: ovx rats; bone; osteoporotic bone; bone defect ... See more keywords