Interplay Between Long Noncoding RNA ZEB1‐AS1 and miR‐200s Regulates Osteosarcoma Cell Proliferation and Migration
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DOI: 10.1002/jcb.25879
Abstract: In our previous study, we found long noncoding RNA ZEB1‐AS1 is upregulated and functions as an oncogene in osteosarcoma. MiR‐200 family (miR‐200s) functions as tumor suppressor via directly targeting ZEB1 in various cancers. In this… read more here.
Keywords: as1 mir; mir 200s; zeb1 as1; zeb1 ... See more keywords
Osteosarcoma cell death induced by innovative scaffolds doped with chemotherapeutics
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DOI: 10.1002/jcp.31256
Abstract: Osteosarcoma (OS) cancer treatments include systemic chemotherapy and surgical resection. In the last years, novel treatment approaches have been proposed, which employ a drug‐delivery system to prevent offside effects and improves treatment efficacy. Locally delivering… read more here.
Keywords: osteosarcoma cell; delivery system; drug; cell ... See more keywords
Betulin inhibits mTOR and induces autophagy to promote apoptosis in human osteosarcoma cell lines
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DOI: 10.1002/tox.22924
Abstract: Betulin is a lupane type pentacyclic triterpenoid, and commonly found in the bark of birch trees. It displays various pharmacological properties, such as antibacterial, anti‐inflammation, antitumor, and antiviral. In this report, we attempted to investigate… read more here.
Keywords: cell lines; mtor; osteosarcoma cell; betulin ... See more keywords
Acute generation of reactive oxygen species that induced by doxycycline pretreatment results in rapid cell death in polyphyllin G‐treated osteosarcoma cell lines
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DOI: 10.1002/tox.23757
Abstract: Polyphyllin G, a pennogenyl saponin extracted from Paris polyphylla, has been shown to possess antitumor effects. In this study, we demonstrated that doxycycline, an antibiotic medicine, could significantly enhance the sensitivities of osteosarcoma cell lines… read more here.
Keywords: cell death; cell; osteosarcoma cell; polyphyllin ... See more keywords
Urolithin A suppressed osteosarcoma cell migration and invasion via targeting MMPs and AKT1
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DOI: 10.1038/s41598-025-11804-2
Abstract: Osteosarcoma is an aggressive malignancy marked by a high incidence of local recurrence and distant metastasis, leading to poor outcomes in advanced stages. While current therapies offer long-term survival primarily for patients with localized disease,… read more here.
Keywords: osteosarcoma; migration invasion; cell; osteosarcoma cell ... See more keywords
Baicalin induces apoptosis in human osteosarcoma cell through ROS-mediated mitochondrial pathway
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DOI: 10.1080/14786419.2017.1359173
Abstract: Abstract Baicalin is extracted from a traditional Chinese herb, Scutellaria baicalensis. In this study, the anticancer activity and underlying mechanisms of baicalin towards human osteosarcoma cell (HOS) were investigated. Baicalin could inhibit HOS cell proliferation… read more here.
Keywords: baicalin; osteosarcoma cell; apoptosis human; cell ... See more keywords
Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line
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DOI: 10.1097/cad.0000000000000901
Abstract: Different types of tumors often present an overexpression of cyclooxygenase-2. The aim of this study was to evaluate the effects of parecoxib (NSAID, cyclooxygenase-2 selective inhibitor) in the behavior of the human osteosarcoma MG-63 cell… read more here.
Keywords: cell line; parecoxib; osteosarcoma cell; cell ... See more keywords
Retracted: circSMARCA5 Promoted Osteosarcoma Cell Proliferation, Adhesion, Migration, and Invasion through a Competing Endogenous RNA Network
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DOI: 10.1155/2024/9894810
Abstract: [This retracts the article DOI: 10.1155/2020/2539150.]. read more here.
Keywords: osteosarcoma cell; retracted circsmarca5; cell proliferation; circsmarca5 promoted ... See more keywords
Abstract 2638: Study of the effect of ribosomal protein L23 on the metastasis related protein of human osteosarcoma cell lines
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DOI: 10.1158/1538-7445.am2025-2638
Abstract: Lung metastases are the main cause of death and poor prognosis in patients with osteosarcoma. Its high propensity to metastasize is the leading cause for treatment failure and poor prognosis. Human ribosomal protein L23 (RPL23),… read more here.
Keywords: cell lines; osteosarcoma cell; osteosarcoma; ribosomal protein ... See more keywords
Abstract B031: Isolation and characterization of extracellular vesicles and nanoparticles from osteosarcoma cell lines: Unveiling supermeres and exomeres for therapeutic insights
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DOI: 10.1158/1538-7445.pediatric24-b031
Abstract: Objective: Osteosarcoma, a malignant bone tumor derived from osteoblasts, the cells responsible for bone formation, commonly affects adolescents but can also arise in older individuals. Treatment typically involves a combination of surgical procedures and chemotherapy… read more here.
Keywords: extracellular vesicles; isolation characterization; cell lines; osteosarcoma cell ... See more keywords
Characterization of five newly derived canine osteosarcoma cell lines
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DOI: 10.1186/s12917-019-2099-y
Abstract: BackgroundCanine and human osteosarcomas (OS) are notably similar and have a high rate of metastasis. There is a poor understanding of the tumor development process, predisposing causes, and varying levels of aggression among different cell… read more here.
Keywords: canine osteosarcoma; cell lines; cell; osteosarcoma cell ... See more keywords