Re‐calculating! Navigating through the osteosarcoma treatment roadblock
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2016.12.004
Abstract: Graphical abstract Figure. No Caption available. Abstract The survival rates for patients with osteosarcoma have remained almost static for the past three decades. Current standard of care therapy includes chemotherapies such as doxorubicin, cisplatin, and… read more here.
Keywords: osteosarcoma treatment; calculating navigating; treatment roadblock; navigating osteosarcoma ... See more keywords
Targeted Delivery of Chemotherapeutic Agents for Osteosarcoma Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.843345
Abstract: Since osteosarcoma (OS) is an aggressive bone cancer with unknown molecular pathways of etiology and pathophysiology, improving patient survival has long been a challenge. The conventional therapy is a complex multidisciplinary management that include radiotherapy,… read more here.
Keywords: delivery chemotherapeutic; agents osteosarcoma; targeted delivery; chemotherapeutic agents ... See more keywords
Identification of Gαi3 as a promising target for osteosarcoma treatment
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DOI: 10.7150/ijbs.68861
Abstract: Sustained activation of multiple receptor tyrosine kinases (RTKs) simultaneously is vital for tumorigenesis and progression of osteosarcoma (OS). Gαi proteins recruitment to various RTKs mediates downstream oncogenic signaling activation. The expression, functions and underlying mechanisms… read more here.
Keywords: identification promising; target osteosarcoma; promising target; primary cells ... See more keywords
Recent advances of drug delivery nanocarriers in osteosarcoma treatment
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DOI: 10.7150/jca.36588
Abstract: Osteosarcoma is the most common primary malignant bone tumor mainly occurred in children and adolescence, and chemotherapy is limited for the side effects and development of drug resistance. Advances in nanotechnology and knowledge of cancer… read more here.
Keywords: drug delivery; delivery; drug; osteosarcoma treatment ... See more keywords