Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma
Sign Up to like & getrecommendations! Published in 2020 at "Science Signaling"
DOI: 10.1126/scisignal.aax0273
Abstract: A compound derived from a traditional Chinese medicine targets a phosphodiesterase to induce airway relaxation. Breathing better with osthole β2-Adrenoreceptor agonists used to acutely relieve airway constriction in asthmatic patients become less effective with repeated… read more here.
Keywords: derived traditional; medicine; relaxation; airway relaxation ... See more keywords
Computational Screening of the Natural Product Osthole and Its Derivates for Anti-Inflammatory Activity
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DOI: 10.3390/life12040505
Abstract: Osthole (OS) is a natural coumarin with a long history of medicinal use in a variety of diseases, such as itch and menstrual disorders. In recent years, OS has been shown to treat inflammation and… read more here.
Keywords: product osthole; osthole; computational screening; activity ... See more keywords
Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo
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DOI: 10.3390/nu9060588
Abstract: Anabolic anti-osteoporotic agents are desirable for treatment and prevention of osteoporosis and fragility fractures. Osthole is a coumarin derivative extracted from the medicinal herbs Cnidium monnieri (L.) Cusson and Angelica pubescens Maxim.f. Osthole has been… read more here.
Keywords: osteogenesis osteoblasts; osthole; camp creb; camp ... See more keywords