Osthole-Mediated Inhibition of Neurotoxicity Induced by Ropivacaine via Amplification of the Cyclic Adenosine Monophosphate Signaling Pathway
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DOI: 10.1177/15593258221088092
Abstract: Background Ropivacaine is widely used for clinical anesthesia and postoperative analgesia. However, the neurotoxicity induced by ropivacaine in a concentration- and duration-dependent manner, and it is difficult to prevent neurotoxicity. Osthole inhibits phosphodiesterase-4 activity by… read more here.
Keywords: induced ropivacaine; signaling pathway; mediated inhibition; neurotoxicity ... See more keywords