A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00302-18
Abstract: Transcription factor GATA3 plays vital roles in inner ear development, while regulatory mechanisms controlling its inner ear-specific expression are undefined. We demonstrate that a cis-regulatory element lying 571 kb 3′ to the Gata3 gene directs… read more here.
Keywords: inner ear; gata3; ear specific; gata3 expression ... See more keywords
Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle.
Sign Up to like & getrecommendations! Published in 2023 at "Cell reports"
DOI: 10.2139/ssrn.4119740
Abstract: An abundance of research has recently highlighted the susceptibility of cochleovestibular ganglion (CVG) neurons to noise damage and aging in the adult cochlea, resulting in hearing deficits. Furthering our understanding of the transcriptional cascades that… read more here.
Keywords: otic vesicle; dynamics delaminating; delaminating neuroblasts; transcriptional dynamics ... See more keywords