S-Nitrosylation of OTUB1 Alters Its Stability and Ubc13 Binding.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00855
Abstract: S-Nitrosylation is a reversible post-translational modification that regulates protein function involving the covalent attachment of the nitric oxide (NO) moiety to sulfhydryl residues of the protein. It is an important regulator in the cell signaling… read more here.
Keywords: nitrosylation; otub1; otub1 alters; stability ubc13 ... See more keywords
The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-3037
Abstract: Although cell-cycle arrest, senescence, and apoptosis are established mechanisms of tumor suppression, accumulating evidence reveals that ferroptosis, an iron-dependent, nonapoptotic form of cell death, represents a new regulatory pathway in suppressing tumor development. Ferroptosis is… read more here.
Keywords: otub1; cancer; stability; ferroptosis ... See more keywords