Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1
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DOI: 10.3390/antiox12020350
Abstract: Protein ubiquitination, which is catalyzed by ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases, is a crucial post-translational modification to regulate numerous cellular functions in a spatio–temporal-specific manner. The human genome encodes ~100 deubiquitinating enzymes (DUBs),… read more here.
Keywords: pleiotropic roles; associated deubiquitinase; otud1; roles keap1 ... See more keywords