OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity
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DOI: 10.1080/15548627.2022.2026098
Abstract: ABSTRACT Deubiquitination plays an important role in the regulation of the crosstalk between macroautophagy/autophagy and innate immune signaling, yet its regulatory mechanisms are not fully understood. Here we identify the deubiquitinase OTUD7B as a negative… read more here.
Keywords: irf3 degradation; otud7b; sqstm1 p62; antiviral immunity ... See more keywords