OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2026098
Abstract: ABSTRACT Deubiquitination plays an important role in the regulation of the crosstalk between macroautophagy/autophagy and innate immune signaling, yet its regulatory mechanisms are not fully understood. Here we identify the deubiquitinase OTUD7B as a negative… read more here.
Keywords: irf3 degradation; otud7b; sqstm1 p62; antiviral immunity ... See more keywords
Prognostic Significance of Deubiquitinase OTUD7B in NK/T-Cell Lymphoma.
Sign Up to like & getrecommendations! Published in 2025 at "Asia-Pacific journal of clinical oncology"
DOI: 10.1111/ajco.70060
Abstract: AIM OTUD7B (ovarian tumor domain-containing 7B) is a deubiquitinase that has established prognostic significance in diffuse large B-cell lymphoma and various solid tumors. In our present work, we aimed to explore its role in NK/T… read more here.
Keywords: otud7b; prognostic significance; deubiquitinase; cell lymphoma ... See more keywords