Articles with "otx2" as a keyword



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Otx2 promotes granule cell precursor proliferation and Shh-dependent medulloblastoma maintenance in vivo

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Published in 2018 at "Oncogenesis"

DOI: 10.1038/s41389-018-0070-6

Abstract: The developmental gene OTX2 is expressed by cerebellar granule cell precursors (GCPs), a cell population which undergoes massive expansion during the early postnatal period in response to sonic hedgehog (Shh). GCPs are thought to be… read more here.

Keywords: granule cell; otx2; proliferation; shh dependent ... See more keywords