Monitoring Drug Safety in Pregnancy with Scan Statistics: A Comparison of Two Study Designs
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DOI: 10.1097/ede.0000000000001561
Abstract: Background: Traditional surveillance of adverse infant outcomes following maternal medication exposures relies on pregnancy exposure registries, which are often underpowered. We characterize the statistical power of TreeScan, a data mining tool, to identify potential signals… read more here.
Keywords: outcome definition; bernoulli model; power; pregnancy ... See more keywords