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Published in 2019 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2019.1633657
Abstract: ABSTRACT Personalized medicine has received increasing attentions among scientific communities in recent years. Because patients often have heterogenous responses to treatments, discovering individualized treatment rules (ITR) is an important component of precision medicine. To that…
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Keywords:
individualized treatment;
medicine;
treatment rules;
treatment ... See more keywords
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Published in 2022 at "Journal of Computational and Graphical Statistics"
DOI: 10.1080/10618600.2022.2067552
Abstract: Abstract Individualized treatment rules (ITRs) recommend treatments that are tailored specifically according to each patient’s own characteristics. It can be challenging to estimate optimal ITRs when there are many features, especially when these features have…
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Keywords:
individualized treatment;
outcome weighted;
optimal itrs;
weighted learning ... See more keywords
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Published in 2019 at "Biometrics"
DOI: 10.1111/biom.13084
Abstract: Individualized treatment regimes (ITRs) aim to recommend treatments based on patient-specific characteristics in order to maximize the expected clinical outcome. Outcome weighted learning approaches have been proposed for this optimization problem with primary focus on…
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Keywords:
individualized treatment;
outcome;
treatment;
outcome weighted ... See more keywords