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   Articles with "outer capsid" as a keyword



Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-95256-8

Abstract: Rotaviral gastroenteritis remains a major global health concern, particularly for infants and young children under five years old. Prior to the introduction of the WHO-prequalified rotavirus vaccine, rotavirus (RV) was responsible for approximately 800,000 child… read more here.

Keywords: outer capsid; rotavirus; capsid proteins; multi epitope ... See more keywords

Strain-specific differences in reovirus infection of murine macrophages segregate with polymorphisms in viral outer-capsid protein σ3

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recommendations! Published in 2024 at "Journal of Virology"

DOI: 10.1128/jvi.01147-24

Abstract: ABSTRACT Mammalian orthoreovirus (reovirus) strains type 1 Lang (T1L) and type 3 Dearing-RV (T3D-RV) infect the intestine in mice but differ in the induction of inflammatory responses. T1L infection is associated with the blockade of… read more here.

Keywords: oral immunological; reovirus; outer capsid; immunological tolerance ... See more keywords

Increased Clinical Signs and Mortality in IFNAR(−/−) Mice Immunised with the Bluetongue Virus Outer-Capsid Proteins VP2 or VP5, after Challenge with an Attenuated Heterologous Serotype

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recommendations! Published in 2023 at "Pathogens"

DOI: 10.3390/pathogens12040602

Abstract: Bluetongue is an economically important disease of domesticated and wild ruminants caused by bluetongue virus (BTV). There are at least 36 different serotypes of BTV (the identity of which is determined by its outer-capsid protein… read more here.

Keywords: serotype; outer capsid; btv; mice immunised ... See more keywords

Molecular Characterization of Outer Capsid Proteins VP5 and VP7 of Grass Carp Reovirus

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recommendations! Published in 2022 at "Viruses"

DOI: 10.3390/v14051032

Abstract: Aquareovirus, which is a member of the Reoviridae family, was isolated from aquatic animals. A close molecular evolutionary relationship between aquareoviruses and mammalian orthoreoviruses was revealed. However, the functions of the aquareovirus genome-encoded proteins are… read more here.

Keywords: vp7 grass; vp5 vp7; capsid proteins; outer capsid ... See more keywords