Tryptophan 375 stabilizes the outer-domain core of gp120 for HIV vaccine immunogen design
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DOI: 10.1016/j.vaccine.2017.04.054
Abstract: Highlights • VRC01 epitope focused structure-based immunogen design.• Gp120 outer-domain core was further stabilized by 375 tryptophan substitution.• Epitope specific antibodies were predominately induced through guinea pig immunizations. read more here.
Keywords: gp120; domain core; outer domain; immunogen design ... See more keywords