Cell cycle control of kinetochore assembly
Sign Up to like & getrecommendations! Published in 2022 at "Nucleus"
DOI: 10.1080/19491034.2022.2115246
Abstract: ABSTRACT The kinetochore is a large proteinaceous structure assembled on the centromeres of chromosomes. The complex machinery links chromosomes to the mitotic spindle and is essential for accurate chromosome segregation during cell division. The kinetochore… read more here.
Keywords: kinetochore; cell cycle; control kinetochore; cycle control ... See more keywords
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system
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DOI: 10.1091/mbc.e23-08-0325
Abstract: The KMN (Knl1/Mis12/Ndc80) network at the kinetochore, primarily known for its role in chromosome segregation, has been shown to be repurposed during neurodevelopment. Here, we investigate the underlying neuronal mechanism and show that the KMN… read more here.
Keywords: system; nervous system; cell; outer kinetochore ... See more keywords
Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.862637
Abstract: The assembly of a functional kinetochore on centromeric chromatin is necessary to connect chromosomes to the mitotic spindle, ensuring accurate chromosome segregation. This connecting function of the kinetochore presents multiple internal and external structural challenges.… read more here.
Keywords: kinetochore; across evolution; linker; centromeric chromatin ... See more keywords