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   Articles with "outer mitochondrial" as a keyword



Redox-dependent gating of VDAC by mitoNEET

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recommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1908271116

Abstract: Significance This work demonstrates that the outer mitochondrial-anchored [2Fe-2S] mitoNEET is able to bind within the central cavity of the voltage-dependent anion channel (VDAC) and regulate its gating in a redox-dependent manner. These findings have… read more here.

Keywords: mitoneet; mitoneet redox; vdac; outer mitochondrial ... See more keywords

Dual-localized PPTC7 limits mitophagy through proximal and dynamic interactions with BNIP3 and NIX

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recommendations! Published in 2024 at "Life Science Alliance"

DOI: 10.26508/lsa.202402765

Abstract: The mitochondrial phosphatase PPTC7 was previously found to suppress mitophagy, but the underlying mechanisms were unclear. Here, the authors show that PPTC7 dynamically localizes to the outer mitochondrial membrane to promote the turnover of the… read more here.

Keywords: dual localized; outer mitochondrial; mitochondrial membrane; bnip3 nix ... See more keywords

Identification of Novel Interaction Partners of AIF Protein on the Outer Mitochondrial Membrane

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recommendations! Published in 2018 at "Acta Naturae"

DOI: 10.32607/20758251-2018-10-4-100-109

Abstract: In response to the wide variety of external and internal signals, mammalian cells undergo apoptosis, programmed cell death. Dysregulation of apoptosis is involved in multiple human diseases, including cancer, autoimmunity, and ischemic injuries. Two types… read more here.

Keywords: apoptosis; aif protein; outer mitochondrial; mortalin ... See more keywords
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Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

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recommendations! Published in 2020 at "Toxins"

DOI: 10.3390/toxins12070425

Abstract: Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via… read more here.

Keywords: cobra venom; outer mitochondrial; bilayer; mitochondrial membrane ... See more keywords