Redox-dependent gating of VDAC by mitoNEET
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1908271116
Abstract: Significance This work demonstrates that the outer mitochondrial-anchored [2Fe-2S] mitoNEET is able to bind within the central cavity of the voltage-dependent anion channel (VDAC) and regulate its gating in a redox-dependent manner. These findings have… read more here.
Keywords: mitoneet; mitoneet redox; vdac; outer mitochondrial ... See more keywords
Identification of Novel Interaction Partners of AIF Protein on the Outer Mitochondrial Membrane
Sign Up to like & getrecommendations! Published in 2018 at "Acta Naturae"
DOI: 10.32607/20758251-2018-10-4-100-109
Abstract: In response to the wide variety of external and internal signals, mammalian cells undergo apoptosis, programmed cell death. Dysregulation of apoptosis is involved in multiple human diseases, including cancer, autoimmunity, and ischemic injuries. Two types… read more here.
Keywords: apoptosis; aif protein; outer mitochondrial; mortalin ... See more keywords
Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane
Sign Up to like & getrecommendations! Published in 2020 at "Toxins"
DOI: 10.3390/toxins12070425
Abstract: Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via… read more here.
Keywords: cobra venom; outer mitochondrial; bilayer; mitochondrial membrane ... See more keywords