Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cell stem cell"
DOI: 10.1016/j.stem.2019.11.015
Abstract: Glioblastoma is a devastating form of brain cancer. To identify aspects of tumor heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor cell atlas with single-cell transcriptomics of cancer cells mapped… read more here.
Keywords: radial glia; glioblastoma; outer radial; cancer ... See more keywords
A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206147119
Abstract: The neocortex, the center for higher brain function, first emerged in mammals and has become massively expanded and folded in humans, constituting almost half the volume of the human brain. Primary microcephaly, a developmental disorder… read more here.
Keywords: function; neocortical folding; kinase; outer radial ... See more keywords