Interactions between Curcumin Derivatives and Amyloid-β Fibrils: Insights from Molecular Dynamics Simulations
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DOI: 10.1021/acs.jcim.9b00561
Abstract: The aggregation of amyloid-β (Aβ) peptides into senile plaques is a hallmark of Alzheimer’s disease (AD) and is hypothesized to be the primary cause of AD related neurodegeneration. Previous studies have shown the ability of… read more here.
Keywords: outermost peptide; molecular dynamics; curcumin derivatives; partial dissociation ... See more keywords