Tissue plasminogen activator attenuates outflow facility reduction in mouse model of juvenile open angle glaucoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108179
Abstract: Tissue plasminogen activator (tPA) has been shown to prevent steroid-induced reduction in aqueous humor outflow facility via an upregulation in matrix metalloproteinase (Mmp) expression. The purpose of this study was to determine whether tPA can… read more here.
Keywords: tpa; facility; outflow facility; facility reduction ... See more keywords
Transgene expression of Stanniocalcin-1 provides sustained intraocular pressure reduction by increasing outflow facility
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DOI: 10.1371/journal.pone.0269261
Abstract: Glaucoma is the leading cause of irreversible blindness worldwide. Therapies for glaucoma are directed toward reducing intraocular pressure (IOP), the leading risk factor and only reliable therapeutic target via topical medications or with procedural intervention… read more here.
Keywords: stanniocalcin; outflow facility; iop; expression ... See more keywords
A portable feedback-controlled pump for monitoring eye outflow facility in conscious rats
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DOI: 10.1371/journal.pone.0280332
Abstract: Intraocular pressure (IOP) is heavily influenced by the resistance of trabecular outflow pathways through which most of the aqueous humor produced by the eye continuously drains. The standard method of quantifying outflow resistance and other… read more here.
Keywords: facility; outflow facility; eye; pressure ... See more keywords