Reelin activates the small GTPase TC10 and VAMP7 to promote neurite outgrowth and regeneration of dorsal root ganglia (DRG) neurons
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24688
Abstract: Axonal outgrowth is a fundamental process during the development of central (CNS) and peripheral (PNS) nervous system as well as in nerve regeneration and requires accurate axonal navigation and extension to the correct target. These… read more here.
Keywords: outgrowth; regeneration; drg neurons; dorsal root ... See more keywords
Exogenous application of GA3 inactively regulates axillary bud outgrowth by influencing of branching-inhibitors and bud-regulating hormones in apple (Malus domestica Borkh.)
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics and Genomics"
DOI: 10.1007/s00438-018-1481-y
Abstract: Although gibberellin (GA) has been reported to control branching, little is known about how GA mediates signals regulating the outgrowth of axillary buds (ABs). In the current study, the effect of the exogenous application of… read more here.
Keywords: outgrowth; application ga3; bud regulating; exogenous application ... See more keywords
Elevated miR-29a Contributes to Axonal Outgrowth and Neurological Recovery After Intracerebral Hemorrhage via Targeting PTEN/PI3K/Akt Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-020-00945-9
Abstract: Spontaneous intracerebral hemorrhage (ICH) is a clinical challenge with high disability and lacks an effective treatment. miR-29a strongly expressed in the brain has been implicated in various neurological disorders. In this study, we investigated the… read more here.
Keywords: outgrowth neurological; mir 29a; outgrowth; pi3k akt ... See more keywords
Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root ganglia in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.06.049
Abstract: Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs) and electrospun fibers have shown promise in tissue engineering fields. Controlled grafting of SPIONs to the fibers post-electrospinning generates biocompatible magnetic composites without altering desired fiber… read more here.
Keywords: outgrowth; aligned electrospun; electrospun fibers; neurite outgrowth ... See more keywords
Feedback from Tissue Mechanics Self-Organizes Efficient Outgrowth of Plant Organ.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.10.019
Abstract: Plant organ outgrowth superficially appears like the continuous mechanical deformation of a sheet of cells. Yet, how precisely cells as individual mechanical entities can act to morph a tissue reliably and efficiently into three dimensions… read more here.
Keywords: growth; plant; outgrowth; tissue ... See more keywords
Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.01.016
Abstract: Calcineurin/NFAT signaling is active in endothelial cells and is proposed to be an essential component of the tumor angiogenic response. Here, we investigated the role of endothelial calcineurin signaling in vivo in physiological and pathological angiogenesis… read more here.
Keywords: endothelial calcineurin; calcineurin signaling; outgrowth; calcineurin ... See more keywords
ExplantAnalyzer: An advanced automated neurite outgrowth analysis evaluated by means of organotypic auditory neuron explant cultures
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2021.109341
Abstract: BACKGROUND Neuronal outgrowth assays using organotypic explant cultures are commonly utilized to study neuroregenerative and -protective effects of drugs such as neurotrophins. While this approach offers higher organized tissue compared to single cell cultures and… read more here.
Keywords: explantanalyzer advanced; outgrowth; time; evaluation ... See more keywords
A disturbed auxin signaling affects adventitious root outgrowth in Solanum dulcamara under complete submergence.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2018.03.006
Abstract: Flooding negatively affects the growth and even survival of most terrestrial plants. Upon flooding, the excess water quickly decreases the gas exchange between atmosphere and the submerged plant tissues, which leads to oxygen deficiency resulting… read more here.
Keywords: solanum dulcamara; submergence; outgrowth; auxin signaling ... See more keywords
Geniposide ameliorated fluoxetine‐suppressed neurite outgrowth in Neuro2a neuroblastoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.04.003
Abstract: Aim: Fluoxetine (FXT), a selective serotonin reuptake inhibitor (SSRI), is one of the most common psychiatric medications clinically prescribed; while over‐produced serotonin may suppress neurite development. The role of major iridoids like geniposide (GPS) and… read more here.
Keywords: outgrowth; outgrowth neuro2a; neurite outgrowth; neuro2a neuroblastoma ... See more keywords
A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2016.12.009
Abstract: ABSTRACT The inability of neurites to grow and restore neural connections is common to many neurological disorders, including trauma to the central nervous system and neurodegenerative diseases. Therefore, there is need for a robust and… read more here.
Keywords: system; outgrowth; inhibition; model ... See more keywords
Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2016.11.067
Abstract: Neurite outgrowth is crucial for the maturation of neurons and the establishment of anatomical connections during development of the nervous system. We report here that Arhgef1, a RhoA guanine nucleotide exchange factor previously found expressed… read more here.
Keywords: neural progenitor; cortical neural; progenitor cells; outgrowth ... See more keywords