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   Articles with "ovarian cancer" as a keyword



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Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population

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recommendations! Published in 2019 at "JAMA Internal Medicine"

DOI: 10.1001/jamainternmed.2018.5113

Abstract: Importance The risk of malignant ovarian cancer associated with simple cysts is unknown. Objective To quantify the risk of ovarian cancer based on ultrasonographic characteristics of ovarian masses, including simple cysts, in a large unselected… read more here.

Keywords: risk; risk ovarian; ultrasonography findings; ovarian cancer ... See more keywords
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Cost-effectiveness of Maintenance Therapy Based on Molecular Classification Following Treatment of Primary Epithelial Ovarian Cancer in the United States

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recommendations! Published in 2020 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2020.28620

Abstract: Key Points Question Is maintenance therapy after first-line treatment of ovarian cancer cost-effective in the United States? Findings In this economic evaluation of maintenance strategies after first-line ovarian cancer therapy, no maintenance regimen—including olaparib, olaparib-bevacizumab,… read more here.

Keywords: maintenance; cost; ovarian cancer; maintenance therapy ... See more keywords
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Use of Germline BRCA Testing in Patients With Ovarian Cancer and Commercial Insurance

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.42703

Abstract: This cross-sectional study evaluates changes in the rate of germline BRCA testing among patients with ovarian cancer between 2008 and 2018 and analyzes factors associated with testing rates. read more here.

Keywords: patients ovarian; brca testing; germline brca; ovarian cancer ... See more keywords
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Outcomes From Opportunistic Salpingectomy for Ovarian Cancer Prevention

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.47343

Abstract: Key Points Question Is opportunistic salpingectomy associated with fewer than expected ovarian cancers? Findings This population-based cohort study included 25 889 individuals who underwent opportunistic salpingectomy and 32 080 individuals who underwent hysterectomy alone or tubal ligation.… read more here.

Keywords: salpingectomy; opportunistic salpingectomy; ovarian cancers; ovarian cancer ... See more keywords
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Factor Analysis of Health Care Access With Ovarian Cancer Surgery and Gynecologic Oncologist Consultation

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recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.54595

Abstract: Key Points Question Are health care affordability, availability, and accessibility associated with racial and ethnic disparities in consulting a gynecologic oncologist and receiving surgery for ovarian cancer? Findings In this cohort study of 8987 patients,… read more here.

Keywords: gynecologic oncologist; surgery; ovarian cancer; care ... See more keywords
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Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility

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recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.0666

Abstract: Key Points Question Is the association between frequent aspirin use and reduced risk of ovarian cancer modified by genetic susceptibility to ovarian cancer, assessed using a polygenic score (PGS)? Findings In this pooled analysis of… read more here.

Keywords: frequent aspirin; ovarian cancer; cancer; aspirin use ... See more keywords
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Advances in Ovarian Cancer Care and Unmet Treatment Needs for Patients With Platinum Resistance: A Narrative Review.

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recommendations! Published in 2023 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2023.0197

Abstract: Importance Platinum-based chemotherapy has been the standard of care for ovarian cancer for the past 3 decades. Although most patients respond to platinum-based treatment, emergence of platinum resistance in recurrent ovarian cancer is inevitable during… read more here.

Keywords: platinum resistant; ovarian cancer; treatment; resistant ovarian ... See more keywords
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Survival After Hyperthermic Intraperitoneal Chemotherapy and Primary or Interval Cytoreductive Surgery in Ovarian Cancer

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recommendations! Published in 2022 at "JAMA Surgery"

DOI: 10.1001/jamasurg.2022.0143

Abstract: Key Points Question Does hyperthermic intraperitoneal chemotherapy (HIPEC) after primary or interval cytoreductive surgery increase survival in patients with ovarian cancer? Findings In this randomized clinical trial of 184 women with ovarian cancer, among those… read more here.

Keywords: surgery; survival; interval cytoreductive; ovarian cancer ... See more keywords
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Assessing Breast and Ovarian Cancer Risk Prior to Gender-Affirming Surgery.

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recommendations! Published in 2023 at "JAMA surgery"

DOI: 10.1001/jamasurg.2022.5447

Abstract: This Viewpoint discusses the need for assessing the risk of hereditary breast and ovarian cancer in individuals seeking gender-affirming surgery and referring eligible patients to genetic counseling and testing services before surgery. read more here.

Keywords: surgery; breast ovarian; ovarian cancer; risk ... See more keywords
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Exosomal microRNAs as tumor markers in epithelial ovarian cancer

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recommendations! Published in 2018 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12371

Abstract: Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles… read more here.

Keywords: epithelial ovarian; mir; mir 200b; ovarian cancer ... See more keywords
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Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin

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recommendations! Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12419

Abstract: Ovarian cancer stem cells (OCSCs) are sources of tumor chemoresistance and recurrence. A hypoxic microenvironment contributes to the chemoresistance of cancer stem cells (CSCs), but the underlying mechanism is not fully understood yet. Here, we… read more here.

Keywords: hif; cancer stem; resistance; expression ... See more keywords