Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1724
Abstract: NUCOLL43 is a novel ovarian clear cell carcinoma (O‐CCC) cell line that arose from a primary culture of a patient's malignant ascites. The cells grow reliably in cell culture with a doubling time of approx.… read more here.
Keywords: original tumor; cell; cell line; ovarian clear ... See more keywords
Diagnostic efficacy of ascites cell block for ovarian clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24734
Abstract: Ascites cytology is important for determining the stage and treatment methods for ovarian clear cell carcinoma (CCC) as defined by the 2014 International Federation of Obstetrics and Gynecology classification. read more here.
Keywords: diagnostic efficacy; cell carcinoma; clear cell; ovarian clear ... See more keywords
Immune‐Hot tumor features associated with recurrence in early‐stage ovarian clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34428
Abstract: Ovarian clear cell carcinoma (OCCC) is a distinct histotype of ovarian cancer, which usually presages a worse prognosis upon recurrence. Identifying patients at risk for relapse is an unmet need to improve outcomes. A retrospective… read more here.
Keywords: hot tumor; immune hot; early stage; ovarian clear ... See more keywords
Management and clinical outcomes of patients with recurrent/progressive ovarian clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.11.018
Abstract: BACKGROUND/PURPOSE Ovarian clear cell carcinoma (OCCC) with recurrence/progression after treatment has dismal prognosis. We aimed to investigate the management and outcomes of such patients. METHODS OCCC patients who were treated between 2000 and 2013 with… read more here.
Keywords: recurrence; cell carcinoma; treatment; ovarian clear ... See more keywords
Prognostic impact of interleukin-6 expression in stage I ovarian clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2017.06.027
Abstract: OBJECTIVE Ovarian clear cell carcinoma (OCCC) frequently presents at an early stage. In stage I OCCC, the prognosis differs according to substage. In particular, predictive biomarkers and new treatment strategies are needed for stage IC2/IC3… read more here.
Keywords: ovarian clear; expression; stage; clear cell ... See more keywords
Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.228
Abstract: Background:Ovarian clear cell carcinoma (OCCC) is mostly resistant to standard chemotherapy that results in poor patient survival. To understand the genetic background of these tumours, we performed whole-genome sequencing of OCCC tumours.Methods:Tumour tissue samples and… read more here.
Keywords: whole genome; cell carcinoma; ovarian clear; genome sequencing ... See more keywords
Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of cancer"
DOI: 10.1038/s41416-022-01808-4
Abstract: BACKGROUND Serum starvation and hypoxia (SSH) mimics a stress condition in tumours. We have shown that intercellular adhesion molecule-1 (ICAM-1) protein is synergistically expressed in ovarian clear cell carcinoma (CCC) cells under SSH in response… read more here.
Keywords: expression; cell carcinoma; ovarian clear; clear cell ... See more keywords
Cytoplasmic EBP50 and elevated PARP1 are unfavorable prognostic factors in ovarian clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Carcinogenesis"
DOI: 10.1093/carcin/bgab070
Abstract: Patients with ovarian clear cell carcinoma (OCCC) experience frequent recurrence, which is most likely due to chemoresistance. We used shotgun proteomics analysis and identified upregulation of ezrin-binding phosphoprotein 50 (EBP50) in recurrent OCCC samples. Cytoplasmic… read more here.
Keywords: ebp50; cell carcinoma; ovarian clear; cytoplasmic ebp50 ... See more keywords
Advanced ovarian clear cell carcinoma with RAD50 mutation treated by PARP inhibitor pamiparib combined with anti-angiogenesis therapy: a case report
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001412
Abstract: Ovarian clear cell carcinoma (OCCC) is a relatively uncommon epithelial ovarian malignancy with unique clinical, histopathologic and genetic characteristics. Patients with advanced OCCC have poor outcomes and are resistant to standard chemotherapy. Targeted therapy offers… read more here.
Keywords: ovarian clear; therapy; report; case ... See more keywords
Ovarian clear cell cancer associated with Trousseau syndrome: A case report and literature review
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DOI: 10.1097/md.0000000000032106
Abstract: Rationale: Trousseau syndrome is known as patients with tumors have a combination of multiple thrombi with systemic organ infarction. The incidence of ovarian clear cell cancer associated with Trousseau syndrome is relatively low. We report… read more here.
Keywords: trousseau syndrome; cell cancer; ovarian clear; clear cell ... See more keywords
Sintilimab combined with bevacizumab in relapsed/persistent ovarian clear cell carcinoma (INOVA): an investigator-initiated, multicentre clinical trial—a study protocol of clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-058132
Abstract: Background Ovarian clear cell carcinoma (OCCC) has an abysmal prognosis with a median overall survival (OS) of 25.3 months because of a low response to chemotherapy. The 5-year disease-specific survival rate after recurrence is 13.2%,… read more here.
Keywords: cell carcinoma; ovarian clear; sintilimab; trial ... See more keywords