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   Articles with "ovarian dysfunction" as a keyword



Hypo-Hydroxymethylation of Nobox is Associated with Ovarian Dysfunction in Rat Offspring Exposed to Prenatal Hypoxia

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recommendations! Published in 2022 at "Reproductive Sciences"

DOI: 10.1007/s43032-022-00866-6

Abstract: Prenatal hypoxia (PH) is a common feature of a suboptimal intrauterine environment affecting the development of fetuses. Whether PH leads to abnormal ovary development is not yet clear. This study investigated ovarian function in offspring… read more here.

Keywords: prenatal hypoxia; hypo hydroxymethylation; offspring exposed; hydroxymethylation ... See more keywords

Crosstalk between advanced glycation end products and vitamin D: A compelling paradigm for the treatment of ovarian dysfunction in PCOS

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recommendations! Published in 2019 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2018.08.010

Abstract: Women with PCOS have elevated levels of the harmful advanced glycation end products (AGEs) and low serum levels of vitamin D. AGEs and their receptors may contribute to the pathogenesis of PCOS and its metabolic… read more here.

Keywords: advanced glycation; pcos; end products; glycation end ... See more keywords

Identification of the first homozygous POLG mutation causing non-syndromic ovarian dysfunction

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recommendations! Published in 2018 at "Climacteric"

DOI: 10.1080/13697137.2018.1467891

Abstract: Abstract Objective: To investigate the genetic cause of non-syndromic ovarian dysfunction in a patient from a consanguineous family. Methods: This study examined a patient with irregular menstrual cycles and abnormal oocytes. The patient had undergone… read more here.

Keywords: polg; dysfunction; syndromic ovarian; non syndromic ... See more keywords
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Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity

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recommendations! Published in 2020 at "Systems Biology in Reproductive Medicine"

DOI: 10.1080/19396368.2020.1780649

Abstract: ABSTRACT Obesity, known to cause a systemic elevation in monocyte chemotactic protein-1 (MCP-1), adversely affects normal ovarian function. The aim of this study was to determine whether MCP-1 plays a role in ovarian dysfunction that… read more here.

Keywords: group; ovarian dysfunction; obesity; monocyte chemotactic ... See more keywords

MicroRNA-146 attenuates lipopolysaccharide induced ovarian dysfunction by inhibiting the TLR4/NF- κB signaling pathway

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2070584

Abstract: ABSTRACT Premature ovarian insufficiency (POI) is a disease that seriously affects women’s reproductive function and even leads to lifelong infertility. Little is known about the mechanism of lipopolysaccharide (LPS)-induced ovarian dysfunction. Thus, we aimed to… read more here.

Keywords: signaling pathway; dysfunction inhibiting; dysfunction; induced ovarian ... See more keywords
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Glycyrrhizin ameliorates impaired glucose metabolism and ovarian dysfunction in a polycystic ovary syndrome mouse model.

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recommendations! Published in 2023 at "Biology of reproduction"

DOI: 10.1093/biolre/ioad048

Abstract: OBJECTIVE The aim of this study was to determine the impact of glycyrrhizin, an inhibitor of high mobility group box 1 (HMGB1), on glucose metabolic disorders and ovarian dysfunction in mice with polycystic ovary syndrome… read more here.

Keywords: polycystic ovary; ovary syndrome; pcos; mice ... See more keywords

Genetic screening in patients with ovarian dysfunction

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recommendations! Published in 2022 at "Clinical Genetics"

DOI: 10.1111/cge.14267

Abstract: Ovarian dysfunction, including premature ovarian insufficiency and decreased ovarian reserve, affects the ovarian reserve and is one of the leading causes of female infertility. More and more cases of ovarian dysfunction are associated with genetic… read more here.

Keywords: patients ovarian; dysfunction; ovarian dysfunction; genetic screening ... See more keywords

Ovarian fibrosis: molecular mechanisms and potential therapeutic targets

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recommendations! Published in 2024 at "Journal of Ovarian Research"

DOI: 10.1186/s13048-024-01448-7

Abstract: Ovarian fibrosis, characterized by the excessive proliferation of ovarian fibroblasts and the accumulation of extracellular matrix (ECM), serves as one of the primary causes of ovarian dysfunction. Despite the critical role of ovarian fibrosis in… read more here.

Keywords: ovarian fibrosis; fibrosis; potential therapeutic; ovarian dysfunction ... See more keywords

Cancer Treatment-Related Ovarian Dysfunction in Women of Childbearing Potential: Management and Fertility Preservation Options

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recommendations! Published in 2023 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.22.01885

Abstract: PURPOSE To review the complex concerns of oncofertility created through increased cancer survivorship and the long-term effects of cancer treatment in young adults. DESIGN Review chemotherapy-induced ovarian dysfunction, outline how fertility may be addressed before… read more here.

Keywords: cancer treatment; fertility; dysfunction; ovarian dysfunction ... See more keywords

Ovarian dysfunction in women with Turner syndrome

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recommendations! Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1160258

Abstract: Ovarian dysfunction is one of the most common features of women with Turner syndrome. In these women, oocyte apoptosis is markedly accelerated from the early stage of fetal life. Reduction in the number of germ… read more here.

Keywords: women turner; dysfunction women; ovarian dysfunction; turner syndrome ... See more keywords

Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice

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recommendations! Published in 2025 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2025.1595602

Abstract: The increasing prevalence of depression profoundly affects female ovarian health. Although Cuscutae Semen (CS) is acknowledged for treating reproductive disorders, its pharmacological mechanisms in depression-induced ovarian dysfunction remain insufficiently explored. This study investigated CS’s effects… read more here.

Keywords: mice; induced ovarian; ovarian dysfunction; depression ... See more keywords