Hypo-Hydroxymethylation of Nobox is Associated with Ovarian Dysfunction in Rat Offspring Exposed to Prenatal Hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Sciences"
DOI: 10.1007/s43032-022-00866-6
Abstract: Prenatal hypoxia (PH) is a common feature of a suboptimal intrauterine environment affecting the development of fetuses. Whether PH leads to abnormal ovary development is not yet clear. This study investigated ovarian function in offspring… read more here.
Keywords: prenatal hypoxia; hypo hydroxymethylation; offspring exposed; hydroxymethylation ... See more keywords
Crosstalk between advanced glycation end products and vitamin D: A compelling paradigm for the treatment of ovarian dysfunction in PCOS
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2018.08.010
Abstract: Women with PCOS have elevated levels of the harmful advanced glycation end products (AGEs) and low serum levels of vitamin D. AGEs and their receptors may contribute to the pathogenesis of PCOS and its metabolic… read more here.
Keywords: advanced glycation; pcos; end products; glycation end ... See more keywords
Identification of the first homozygous POLG mutation causing non-syndromic ovarian dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Climacteric"
DOI: 10.1080/13697137.2018.1467891
Abstract: Abstract Objective: To investigate the genetic cause of non-syndromic ovarian dysfunction in a patient from a consanguineous family. Methods: This study examined a patient with irregular menstrual cycles and abnormal oocytes. The patient had undergone… read more here.
Keywords: polg; dysfunction; syndromic ovarian; non syndromic ... See more keywords
Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity
Sign Up to like & getrecommendations! Published in 2020 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2020.1780649
Abstract: ABSTRACT Obesity, known to cause a systemic elevation in monocyte chemotactic protein-1 (MCP-1), adversely affects normal ovarian function. The aim of this study was to determine whether MCP-1 plays a role in ovarian dysfunction that… read more here.
Keywords: group; ovarian dysfunction; obesity; monocyte chemotactic ... See more keywords
MicroRNA-146 attenuates lipopolysaccharide induced ovarian dysfunction by inhibiting the TLR4/NF- κB signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2070584
Abstract: ABSTRACT Premature ovarian insufficiency (POI) is a disease that seriously affects women’s reproductive function and even leads to lifelong infertility. Little is known about the mechanism of lipopolysaccharide (LPS)-induced ovarian dysfunction. Thus, we aimed to… read more here.
Keywords: signaling pathway; dysfunction inhibiting; dysfunction; induced ovarian ... See more keywords
Glycyrrhizin ameliorates impaired glucose metabolism and ovarian dysfunction in a polycystic ovary syndrome mouse model.
Sign Up to like & getrecommendations! Published in 2023 at "Biology of reproduction"
DOI: 10.1093/biolre/ioad048
Abstract: OBJECTIVE The aim of this study was to determine the impact of glycyrrhizin, an inhibitor of high mobility group box 1 (HMGB1), on glucose metabolic disorders and ovarian dysfunction in mice with polycystic ovary syndrome… read more here.
Keywords: polycystic ovary; ovary syndrome; pcos; mice ... See more keywords
Genetic screening in patients with ovarian dysfunction
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DOI: 10.1111/cge.14267
Abstract: Ovarian dysfunction, including premature ovarian insufficiency and decreased ovarian reserve, affects the ovarian reserve and is one of the leading causes of female infertility. More and more cases of ovarian dysfunction are associated with genetic… read more here.
Keywords: patients ovarian; dysfunction; ovarian dysfunction; genetic screening ... See more keywords
Cancer Treatment-Related Ovarian Dysfunction in Women of Childbearing Potential: Management and Fertility Preservation Options
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DOI: 10.1200/jco.22.01885
Abstract: PURPOSE To review the complex concerns of oncofertility created through increased cancer survivorship and the long-term effects of cancer treatment in young adults. DESIGN Review chemotherapy-induced ovarian dysfunction, outline how fertility may be addressed before… read more here.
Keywords: cancer treatment; fertility; dysfunction; ovarian dysfunction ... See more keywords
Ovarian dysfunction in women with Turner syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1160258
Abstract: Ovarian dysfunction is one of the most common features of women with Turner syndrome. In these women, oocyte apoptosis is markedly accelerated from the early stage of fetal life. Reduction in the number of germ… read more here.
Keywords: women turner; dysfunction women; ovarian dysfunction; turner syndrome ... See more keywords
Baicalein Ameliorates Chronic Stress-Mediated Ovarian Dysfunction by Upregulating the Expression of Gamma-Aminobutyric Acid B2 Receptor
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DOI: 10.4103/2096-2924.232876
Abstract: Background: The aim of this study is to assess the effect of baicalein on chronic stress-mediated ovarian dysfunction in a mouse model. Methods: Forty female C57BL/6 mice were randomly divided into four groups as follows:… read more here.
Keywords: chronic stress; baicalein; daily stress; group ... See more keywords