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Published in 2021 at "Gynecologic Oncology"
DOI: 10.1016/s0090-8258(21)01249-x
Abstract: Objectives: To identify actionable gene mutations in recurrent ovarian and endometrial cancer and to evaluate the effect of these cancer specific mutations on survival outcomes at a single institution. Methods: This was an institutional review…
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Keywords:
mutations recurrent;
endometrial cancer;
recurrent ovarian;
cancer ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6522
Abstract: Ovarian and endometrial cancers come within the top-4 for incident cancers as well as deaths in North American women. Cure rates have not improved in 30 years as high-grade subtypes continue to be diagnosed in…
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Keywords:
ovarian endometrial;
endometrial cancers;
accurate sequencing;
highly accurate ... See more keywords
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Published in 2023 at "Cancer prevention research"
DOI: 10.1158/1940-6207.capr-22-0374
Abstract: Ovarian and endometrial cancers are the most common gynecologic malignancies and emerging evidence suggests that lipid metabolism and subsequent inflammation are important etiologic factors for both tumors. Statins (HMG-CoA reductase inhibitors) are the most widely…
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Keywords:
ovarian endometrial;
endometrial cancers;
role;
prevention ... See more keywords
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Published in 2020 at "Women's Health"
DOI: 10.1177/1745506520961710
Abstract: Drug repurposing is the application of an existing licenced drug for a new indication and potentially provides a faster and cheaper approach to developing new anti-cancer agents. Gynaecological cancers contribute significantly to the global cancer…
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Keywords:
endometrial cervical;
role aspirin;
cancer;
prevention ... See more keywords
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Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac141
Abstract: Abstract It is well known that many factors, including infertility, obesity, type 2 diabetes, and family history of cancer, increase the risk of developing endometrial and ovarian cancer. However, multiparous women are known to have…
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Keywords:
endometrial cancer;
fetal antigens;
pregnancy protects;
ovarian endometrial ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14021
Abstract: Gynecological cancers are known for being very aggressive at their advanced stages. Indeed, the survival rate of both ovarian and endometrial cancers is very low when diagnosed lately and the success rate of current chemotherapy…
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Keywords:
chemoresistance;
chemoresistance targeted;
ovarian endometrial;
therapies ovarian ... See more keywords
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Published in 2021 at "Clinical hemorheology and microcirculation"
DOI: 10.3233/ch-211134
Abstract: Endometriosis is one of the most common diseases that happen in reproductive women. The main symptoms include ovarian endometrial cyst, pelvic pain, and so on. We report a case of a 23-year-old woman with a…
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Keywords:
sclerotherapy;
endometrial cyst;
ovarian endometrial;
cyst ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14040837
Abstract: The non-canonical Wnt signalling receptor ROR1 is aberrantly expressed in numerous cancers, including ovarian and endometrial cancer. We previously reported that silencing ROR1 could inhibit the proliferation and metastatic potential of ovarian and endometrial cancer…
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Keywords:
zilovertamab;
monoclonal antibody;
cancer cells;
cancer ... See more keywords
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Published in 2020 at "Molecular medicine reports"
DOI: 10.3892/mmr.2020.11466
Abstract: Early diagnosis and therapy in the first stages of a malignant disease is the most crucial factor for successful cancer treatment and recovery. Currently, there is a high demand for novel diagnostic tools that indicate…
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Keywords:
distinguishing microrna;
breast ovarian;
expression;
expression levels ... See more keywords