Ovarian germ cell tumor/mastocytosis with KIT mutation: A unique clinicopathological entity
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.1002/gcc.23000
Abstract: Most tumors are sporadic and originated from somatic mutations. Some rare germline mutations cause familial tumors, often involving multiple tissues or organs. Tumors from somatic mosaicism during embryonic development are extremely rare. We describe here… read more here.
Keywords: ovarian germ; kit; germ; germ cell ... See more keywords
A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Cancer"
DOI: 10.1016/j.ejca.2019.03.001
Abstract: Background Adult guidelines recommend BEP (bleomycin, etoposide, cisplatin) for all ovarian germ cell tumours, causing debilitating toxicities in young patients who will survive long term. Paediatricians successfully reduce toxicities by using lower bleomycin doses and… read more here.
Keywords: chemotherapy; cell tumours; germ cell; ovarian germ ... See more keywords
High-dose chemotherapy and stem-cell rescue for salvage therapy for relapsed malignant mixed ovarian germ cell tumor: A case report
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2017.09.013
Abstract: Background Malignant ovarian germ cell tumors are rare, and often treatable with surgery and chemotherapy. Few data are available for treatment of platinum-resistant tumors. Case A 31 year old gravida 0 with a 20 cm… read more here.
Keywords: high dose; ovarian germ; salvage therapy; germ cell ... See more keywords
The impact of lymphadenectomy on prognosis and survival of clinically apparent early-stage malignant ovarian germ cell tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyz180
Abstract: OBJECTIVE To determine the impact of lymphadenectomy (LND) on survival of clinically apparent early-stage malignant ovarian germ cell tumors (MOGCTs). METHODS We retrospectively analyzed the survival of patients who were diagnosed with the three most… read more here.
Keywords: cell tumors; ovarian germ; germ cell; stage ... See more keywords
Paraneoplastic Cytopenia in Ovarian Germ Cell Tumor: A Novel Presentation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001057
Abstract: We report on the case of a 12-year-old girl, who presented with an ovarian germ cell tumor and cytopenia (anemia and thrombocytopenia) as an associated paraneoplastic syndrome, which gradually regressed after the tumor's removal. This… read more here.
Keywords: ovarian germ; cell tumor; germ cell; tumor ... See more keywords
Multidisciplinary management of ovarian germ cell tumours—a single institutional study from India
Sign Up to like & getrecommendations! Published in 2021 at "ecancermedicalscience"
DOI: 10.3332/ecancer.2021.1290
Abstract: Background Ovarian germ cell tumours constitute a heterogeneous group of neoplasm with malignant potential being seen in 5% of cases. There is limited data on treatment outcomes of patients with malignant ovarian germ cell tumours… read more here.
Keywords: ovarian germ; cell tumours; germ cell; histology ... See more keywords
Therapeutic Challenges for Cisplatin-Resistant Ovarian Germ Cell Tumors
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11101584
Abstract: The majority of patients with advanced ovarian germ cell cancer are treated by cisplatin-based chemotherapy. Despite adequate first-line treatment, nearly one third of patients relapse and almost half develop cisplatin-resistant disease, which is often fatal.… read more here.
Keywords: cisplatin resistant; cell; ovarian germ; germ cell ... See more keywords
Molecular Biology of Pediatric and Adult Ovarian Germ Cell Tumors: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15112990
Abstract: Simple Summary Because ovarian germ cell tumors (OGCTs) are rare tumors, our current understanding of them is sparse; this is because few studies have investigated the molecular basis of pediatric and adult cancers. In this… read more here.
Keywords: germ cell; pediatric adult; biology; cell tumors ... See more keywords
Ovarian Germ Cell Tumors: Pictorial Essay
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12092050
Abstract: Ovarian germ cell tumors of the ovary represent a histologically heterogenous group of tumors with a high incidence at reproductive age. Patients with this pathology are very often young women with amenorrhea. The aim of… read more here.
Keywords: germ cell; ovarian germ; pathology; cell tumors ... See more keywords