Three‐dimensional culture of rat ovarian granulosa cells shows increased SPP1 and FGF7 expression through the PI3K/Akt pathway
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11998
Abstract: Ovarian granulosa cells (OGCs) play an essential role in the regulation of follicular growth and development. However, previous studies of OGCs have concentrated on traditional 2D cultures. In the present study, we used the hanging… read more here.
Keywords: culture; pi3k akt; ovarian granulosa; granulosa cells ... See more keywords
Prenatal exposure to bisphenol‐A altered miRNA‐224 and protein expression of aromatase in ovarian granulosa cells concomitant with elevated serum estradiol levels in F1 adult offspring
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22317
Abstract: This study was aimed to predict bisphenol‐A (BPA)‐responsive miRNA's using an in silico approach and to study their expression in granulosa cells of animals exposed prenatally to BPA. Pregnant Wistar rats were exposed to BPA… read more here.
Keywords: ovarian granulosa; granulosa cells; elevated serum; mirna 224 ... See more keywords
Effect of mono‐(2‐ethylhexyl) phthalate (MEHP) on proliferation of and steroid hormone synthesis in rat ovarian granulosa cells in vitro
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DOI: 10.1002/jcp.26224
Abstract: This study aimed to examine the proliferation of and secretion by rat ovarian granulosa cells (GCs) treated with mono‐(2‐ethylhexyl) phthalate (MEHP). Ovarian GCs were incubated with MEHP at concentration of 0, 25, 50, 100, and… read more here.
Keywords: hormone; granulosa cells; ovarian granulosa; mono ethylhexyl ... See more keywords
LRH-1 high expression in the ovarian granulosa cells of PCOS patients
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02774-2
Abstract: Polycystic ovary syndrome (PCOS) is considered one of the most common endocrine disorders with heterogeneity. There are also reports that liver receptor homolog 1 [LRH-1 or nuclear receptor subfamily 5 group A member 2] plays… read more here.
Keywords: expression ovarian; ovarian granulosa; lrh; expression ... See more keywords
N6-methyladenosine Demethylase FTO Induces the Dysfunctions of Ovarian Granulosa Cells by Upregulating Flotillin 2
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DOI: 10.1007/s43032-021-00664-6
Abstract: Polycystic ovarian syndrome (PCOS) is often accompanied by overweight/obesity and insulin resistance. The dysfunctions of ovarian granulosa cells (GCs) are closely linked with the pathogenesis of PCOS. Fat mass and obesity-associated gene (FTO), an N6-methyladenosine… read more here.
Keywords: ovarian granulosa; flot2; insulin resistance; dysfunctions ovarian ... See more keywords
MiR-21-5p actions at the Smad7 gene during pig ovarian granulosa cell apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2020.106645
Abstract: MicroRNAs (miRNAs) are endogenous non-coding RNAs in eukaryotic cells that modulate apoptosis of ovarian granulosa cells (GCs), which is an important cause of mammalian follicular atresia. In the present study, associations were evaluated between miR-21-5p… read more here.
Keywords: ovarian granulosa; mir actions; granulosa cell; apoptosis ... See more keywords
Overexpression of CDC25C affects the cell cycle of ovarian granulosa cells from adult and young goats
Sign Up to like & getrecommendations! Published in 2018 at "Electronic Journal of Biotechnology"
DOI: 10.1016/j.ejbt.2017.10.008
Abstract: Background: CDC25 is a dual-specificity phosphatase that was first identified in the yeast Schizosaccharomyces pombe as a cell cycle-defective mutant. Although CDC25 is involved in the cell cycle of ovarian granulosa cells, the CDC25 signaling… read more here.
Keywords: ovarian granulosa; granulosa cells; granulosa; cdc25c ... See more keywords
Role of adjuvant chemotherapy in the management of stage IC ovarian granulosa cell tumors
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2019.04.004
Abstract: Objective The aim of the present study was to investigate the patterns of use and prognostic significance of adjuvant chemotherapy (CT) for patients with stage IC ovarian granulosa cell tumors (GCTs). Methods We identified patients… read more here.
Keywords: chemotherapy; ovarian granulosa; adjuvant chemotherapy; granulosa cell ... See more keywords
The toxic influence of silver and titanium dioxide nanoparticles on cultured ovarian granulosa cells.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biology"
DOI: 10.1016/j.repbio.2020.100467
Abstract: The application of metal nanoparticles in modern society is growing, but there is insufficient data concerning their influence on reproductive processes and comparison of their biological activity. The present experiments aimed to compare the effects… read more here.
Keywords: ovarian granulosa; granulosa; titanium dioxide; silver titanium ... See more keywords
HERP depletion inhibits zearalenone-induced apoptosis through autophagy activation in mouse ovarian granulosa cells.
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DOI: 10.1016/j.toxlet.2018.10.026
Abstract: HERP is an endoplasmic reticulum (ER) membrane protein and is strongly induced by stress conditions. A recent study has indicated that HERP cooperates in apoptosis during zearalenone (ZEA) treatment. However, regulatory mechanisms and the role… read more here.
Keywords: ovarian granulosa; granulosa cells; granulosa; apoptosis ... See more keywords
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells
Sign Up to like & getrecommendations! Published in 2019 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2019.1658730
Abstract: Abstract The aim of this study was to evaluate the effect of virus infection on estradiol (E2) production in human ovarian granulosa cells. Polyriboinosinic polyribocytidylic acid [Poly (I: C)], a synthetic analog of viral double… read more here.
Keywords: ovarian granulosa; granulosa cells; human ovarian; fsh ... See more keywords