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Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23164
Abstract: As an environmental contaminant, Benzo[a]pyrene (B[a]P; BaP) disrupts the antioxidant signaling and thus leads to the induction of oxidative stress and the damage of DNA in the ovary. low‐dose atorvastatin (ATV) has antioxidant and anti‐apoptotic…
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Keywords:
effect;
benzo pyrene;
ovarian toxicity;
prenatal exposure ... See more keywords
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Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5629
Abstract: Reproductive failure following chemotherapy and/or ionizing radiation is a major adverse event, for which there are no established preventive measures. In previous studies, our laboratory has documented that the selective estrogen receptor modulator, tamoxifen (TAM)…
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Keywords:
system;
tissue;
model;
ovarian toxicity ... See more keywords
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Published in 2019 at "Toxicologic Pathology"
DOI: 10.1177/0192623319877871
Abstract: As ovarian toxicity is often a safety concern for cancer therapeutics, identification of ovarian pathology is important in early stages of preclinical drug development, particularly when the intended patient population include women of child-bearing potential.…
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Keywords:
deep learning;
pathology;
toxicity;
ovarian toxicity ... See more keywords
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Published in 2020 at "Veterinary World"
DOI: 10.14202/vetworld.2020.188-196
Abstract: Background and Aim: Cyclophosphamide therapy is known to be associated with the risk of female infertility as a result of ovarian toxicity. Alpha-lipoic acid (LA) and omega-3 fatty acids are known for their antioxidant and…
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Keywords:
cyclophosphamide induced;
fatty acids;
omega fatty;
ovarian toxicity ... See more keywords
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Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020168
Abstract: The present experiment aimed to identify the potential protective role of empagliflozin (EMPA) on haloperidol (HAL)-induced ovarian damage in female rats because of its anti-inflammatory, antioxidant, and antiapoptotic effects. EMPA was administered in the presence…
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Keywords:
inflammatory apoptotic;
oxidative stress;
ovarian toxicity;
group ... See more keywords