The diagnostic value of magnetic resonance imaging in differentiating benign and malignant pediatric ovarian tumors
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Radiology"
DOI: 10.1007/s00247-020-04871-2
Abstract: The diagnostic workup of ovarian tumors in children and adolescents is challenging because preserving fertility, in addition to oncological safety, is of particular importance in this population. Therefore, a thorough preoperative assessment of ovarian tumors… read more here.
Keywords: ovarian tumors; imaging differentiating; differentiating benign; children adolescents ... See more keywords
Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03905-3
Abstract: Enzymes of the cytochrome P450 (CYP) subfamily 3A and 2C play a major role in the metabolism of taxane anticancer agents. While their function in hepatic metabolism of taxanes is well established, expression of these… read more here.
Keywords: ovarian tumors; lung endometrial; endometrial ovarian; expression ... See more keywords
A clinical review of ovarian tumors in children and adolescents
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Surgery International"
DOI: 10.1007/s00383-020-04660-w
Abstract: Purpose To determine the features which predict torsion and the pre-operative indicators of malignancy in cases of ovarian torsion in ovarian tumors (OTs) in children. Methods The medical records of 35 pediatric patients who underwent… read more here.
Keywords: ovarian tumors; torsion; diagnosis; ovarian torsion ... See more keywords
Possibility of women treated with fertility-sparing surgery for non-epithelial ovarian tumors to safely and successfully become pregnant—a Chinese retrospective cohort study among 148 cases
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers of Medicine"
DOI: 10.1007/s11684-017-0554-3
Abstract: This study was performed to evaluate the oncological and reproductive outcomes of childbearing-age women treated with fertility-sparing surgery (FSS) for non-epithelial ovarian tumors in China. One hundred and forty eight non-epithelial ovarian tumor women treated… read more here.
Keywords: ovarian tumors; epithelial ovarian; histology; women treated ... See more keywords
Management of Borderline Ovarian Tumors: Series of Case Report and Review of the Literature
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DOI: 10.1007/s12262-020-02455-w
Abstract: Borderline ovarian tumors represent a heterogeneous group of tumors with a specific noninvasive histology, a low malignant potential, and an uncertain outcome. They have a low incidence, occurring at younger age and diagnosed in early… read more here.
Keywords: borderline ovarian; management borderline; ovarian tumors; tumors series ... See more keywords
Ovarian tumors orchestrate distinct cellular compositions.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.05.014
Abstract: The determinants of T cell infiltration in tumors remain largely unknown. In a recent issue of Cancer Cell, Hornburg et al. use single-cell RNA sequencing to characterize the cellular compartments of the ovarian cancer microenvironment and shed… read more here.
Keywords: ovarian tumors; tumors orchestrate; orchestrate distinct; distinct cellular ... See more keywords
Borderline Ovarian Tumors: French Guidelines from the CNGOF. Part 1. Epidemiology, Biopathology, Imaging and Biomarkers.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of gynecology obstetrics and human reproduction"
DOI: 10.1016/j.jogoh.2020.101965
Abstract: The incidence (rate per 100 000) of borderline ovarian tumors (BOTs) increases progressively with age, starting at 15-19 years and peaking at around 4.5 cases per 100 000 at an age of 55-59 years (LE3)… read more here.
Keywords: ovarian tumors; use; grade; bot ... See more keywords
Operative management of pediatric ovarian tumors and the challenge of fertility-preservation: Results from the UK CCLG Surgeons Cancer Group Nationwide Study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2020.02.057
Abstract: BACKGROUND Ovarian tumors in the pediatric age group are rare. A significant number of children with ovarian mass lesions present "out of hours "as surgical emergencies, and surgical management does not always involve a surgical… read more here.
Keywords: ovarian tumors; surgery; group; study ... See more keywords
Steroid hormone synthesis by the ovarian stroma surrounding epithelial ovarian tumors: a potential mechanism in ovarian tumorigenesis
Sign Up to like & getrecommendations! Published in 2017 at "Modern Pathology"
DOI: 10.1038/modpathol.2016.219
Abstract: Epithelial ovarian tumors are responsive to steroid hormone stimulation and the ovarian stroma may have a direct role in this process. We evaluated immunohistochemical markers of sex-steroid differentiation and steroidogenesis (calretinin, inhibin, steroidogenic factor 1),… read more here.
Keywords: ovarian tumors; hormone; epithelial ovarian; steroid hormone ... See more keywords
Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Human Genetics"
DOI: 10.1038/s10038-020-0780-4
Abstract: Poly-ADP-ribose-polymerase inhibitor (PARPi) treatment is indicated for advanced-stage ovarian tumors with BRCA1/2 deficiency. The “BRCAness” status is thought to be attributed to a tumor phenotype associated with a specific epigenomic DNA methylation profile. Here, we… read more here.
Keywords: ovarian tumors; methylation; dna; brca1 ... See more keywords
Mural nodules in mucinous ovarian tumors represent a morphologic spectrum of clonal neoplasms: a morphologic, immunohistochemical, and molecular analysis of 13 cases
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0642-9
Abstract: Mucinous ovarian tumors rarely harbor mural nodules, which have historically been classified as sarcoma-like, anaplastic carcinomatous, or sarcomatous on the basis of predominant morphologic features. The molecular relationship between mural nodules and associated mucinous ovarian… read more here.
Keywords: ovarian tumors; mural nodules; sarcoma like; anaplastic carcinomatous ... See more keywords