Articles with "ovariectomized mice" as a keyword



The combined effects of Teriparatide and Anti-RANKL Monoclonal Antibody on Bone Defect Regeneration in Ovariectomized Mice.

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Published in 2019 at "Bone"

DOI: 10.1016/j.bone.2019.115077

Abstract: OBJECTIVE The purpose of this study was to investigate the combined effects of teriparatide (TPTD) and anti-murine receptor activator of nuclear factor-κB ligand monoclonal antibody (anti-RANKL Ab) on both cancellous and cortical bone healing in… read more here.

Keywords: cortical bone; group; regeneration; bone ... See more keywords
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Kamishoyosan potentiates pentobarbital-induced sleep in socially isolated, ovariectomized mice.

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Published in 2021 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2021.114585

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Sleep disorders are among the most common symptoms in both peri- and post-menopausal women. Kamishoyosan (KSS) is a Kampo medicine prescribed for the treatment of sleep disorders in menopausal women in Japan. However,… read more here.

Keywords: pentobarbital induced; socially isolated; ovariectomized mice; sleeping time ... See more keywords
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Long-term oral administration of a novel estrogen receptor beta agonist enhances memory and alleviates drug-induced vasodilation in young ovariectomized mice

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Published in 2021 at "Hormones and Behavior"

DOI: 10.1016/j.yhbeh.2021.104948

Abstract: Development of estrogen therapies targeting the β (ERβ) but not α (ERα) estrogen receptor is critically needed for the treatment of negative menopausal symptoms, as ERα activation increases health risks like cancer. Here, we determined… read more here.

Keywords: agonist; estrogen; vasodilation; ovariectomized mice ... See more keywords
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Encapsulation of ovarian allograft precludes immune rejection and promotes restoration of endocrine function in immune-competent ovariectomized mice

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-53075-8

Abstract: Premature ovarian insufficiency (POI) is a significant complication of cytotoxic treatments due to extreme ovarian sensitivity to chemotherapy and radiation. POI is particularly devastating for young girls reaching puberty, because it irreversibly affects their physical… read more here.

Keywords: endocrine function; immune competent; ovariectomized mice; competent ... See more keywords
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UPLC/Q-TOF-MS-based Metabolomics Study of the Antiosteoporosis Effects of Vaccarin in Ovariectomized Mice

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Published in 2022 at "Planta Medica"

DOI: 10.1055/a-1942-5428

Abstract: Abstract Osteoporosis is a systemic and metabolic bone disease that usually occurs in postmenopausal women, which mainly manifests as bone loss and increased bone fragility that both facilitate fracture. However, few drugs for osteoporosis have… read more here.

Keywords: uplc tof; antiosteoporosis; effects vaccarin; tof based ... See more keywords
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Urethral proteomic analysis in ovariectomized mice administered 17β-oestradiol replacement therapy

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Published in 2017 at "Journal of Obstetrics and Gynaecology"

DOI: 10.1080/01443615.2017.1292225

Abstract: Abstract The molecular mechanism by which 17β-oestradiol (E2) increases urethral tone is unclear. As human tissue is limited in availability, we explored changes in the urethras of ovariectomized (OVX) mice. Twenty-four virgin female mice were… read more here.

Keywords: replacement; ovx mice; tone; ovariectomized mice ... See more keywords
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Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐κB Signaling Pathway

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Published in 2022 at "Orthopaedic Surgery"

DOI: 10.1111/os.13252

Abstract: To investigate the changes in proinflammatory cytokines and chemokines, namely, C‐C motif ligand (CCL) 2 and CCL7, in postmenopausal osteoporosis (PMOP) and to develop a new drug, bindarit (Bnd), for PMOP in an ovariectomized (OVX)… read more here.

Keywords: loss ovariectomized; bone loss; ccl7; ovariectomized mice ... See more keywords
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Jiao-Tai-Wan Ameliorates Depressive-Like Behavior through the A1R Pathway in Ovariectomized Mice after Unpredictable Chronic Stress

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/1507561

Abstract: Objective This study was aimed at observing the effect Jiao-Tai-Wan in menopausal depression. Methods In this paper, we used ovariectomized mice subjected to chronic unpredictable stress as a menopausal depression model. After the chronic stress,… read more here.

Keywords: chronic stress; tai wan; jiao tai; ovariectomized mice ... See more keywords
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Aucubin Impeded Preosteoclast Fusion and Enhanced CD31hi EMCNhi Vessel Angiogenesis in Ovariectomized Mice

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Published in 2022 at "Stem Cells International"

DOI: 10.1155/2022/5226771

Abstract: Osteogenesis is tightly correlated with angiogenesis during the process of bone development, regeneration, and remodeling. In addition to providing nutrients and oxygen for bone tissue, blood vessels around bone tissue also secrete some factors to… read more here.

Keywords: vessel; bone; aucubin impeded; ovariectomized mice ... See more keywords
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Effect of Ethanolic Extracts from Taiwanofungus camphoratus and T. salmoneus (Agaricomycetes) Mycelia on Osteoporosis Recovery.

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Published in 2020 at "International journal of medicinal mushrooms"

DOI: 10.1615/intjmedmushrooms.2020033983

Abstract: Osteoporosis is common in postmenopausal women and elderly people. In this study, the ovariectomized mice were used as an in vivo test to evaluate the effects of 70% ethanolic extracts of Taiwanofungus camphoratus and T.… read more here.

Keywords: bone; camphoratus; ovariectomized mice; extracts taiwanofungus ... See more keywords
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Follicular development and the expression of BAX and vascular endothelial growth factor in transplanted ovaries in uni- and bilateral ovariectomized mice: An experimental study

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Published in 2021 at "International Journal of Reproductive Biomedicine"

DOI: 10.18502/ijrm.v19i4.9062

Abstract: Abstract Background Several conflicting results have been reported on the survival and function of transplanted ovaries. Objective Evaluation of the follicular development and the expression of vascular endothelial growth factor (VEGF) and Bcl-2-associated X protein… read more here.

Keywords: transplanted ovaries; group; ovariectomized mice; expression ... See more keywords