Lupeol, the major compound of the dichloromethane extract of Millettia macrophylla Benth (Fabaceae), displays estrogenic effects in ovariectomized rats
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DOI: 10.1002/ptr.6288
Abstract: The present work deals with the assessment of the in vitro and in vivo estrogenic effects of the triterpenoids (lupenone, lupeol, and stigmastenone) isolated from Millettia macrophylla extract. The in vitro estrogenicity was performed by… read more here.
Keywords: estrogenic effects; millettia macrophylla; lupeol major; ovariectomized rats ... See more keywords
ADAMTS-1, a multifunctional proteinase, in the uterus of both estrous cycle rats and ovariectomized rats can be regulated via hormones
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DOI: 10.1007/s00418-025-02382-5
Abstract: Remodeling of the extracellular matrix (ECM) throughout the estrous cycle is one of the most striking features of the uterus. A disintegrin and metalloprotease with thrombospondin type I motifs (ADAMTS-1) is a metalloproteinase responsible for… read more here.
Keywords: estrous cycle; hormone; ovx group; ovariectomized rats ... See more keywords
Short-term and long-term effects of osteoporosis on incisor teeth and femoral bones evaluated by Raman spectroscopy and energy dispersive X-ray analysis in ovariectomized rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-018-0903-6
Abstract: There are few published data on the relationship between loss of bone mass due to osteoporosis and poor tooth quality. This study analyzed the effects of osteoporosis on incisor teeth and femoral bones using optical… read more here.
Keywords: femoral bones; ovariectomized rats; group; incisor teeth ... See more keywords
The effect of acidic-treated acorn pollen on lipid and antioxidant metabolism with ovariectomized rats
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DOI: 10.1007/s10068-020-00751-5
Abstract: The hormonal imbalance that occurs during menopause increases the risk of aging and chronic diseases. Therefore, this study was intended to improve the health of menopause women by using pollen, which is a natural food,… read more here.
Keywords: effect acidic; ovariectomized rats; metabolism; acidic treated ... See more keywords
Systemic estradiol administration to ovariectomized rats facilitates thermoregulatory behavior in a cold environment
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DOI: 10.1016/j.brainres.2017.06.009
Abstract: Rats place their tails underneath their bodies in the cold (tail-hiding behavior), which is a behavioral indicator of thermoregulation. The aim of the present study was to elucidate the effect of estradiol (E2) on tail-hiding… read more here.
Keywords: systemic estradiol; tail hiding; ovariectomized rats; group ... See more keywords
Cinnamomum burmanini Blume increases bone turnover marker and induces tibia's granule formation in ovariectomized rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2017.01.005
Abstract: Background Bone fragility and an increase in susceptibility to fracture osteoporosis is characterized by a reduction in bone mass and the micro-architectural deterioration of bone tissue. There is no previous study regarding the effect of… read more here.
Keywords: burmanini blume; bone turnover; blume; ovariectomized rats ... See more keywords
Different doses of strontium ranelate and mechanical vibration modulate distinct responses in the articular cartilage of ovariectomized rats.
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DOI: 10.1016/j.joca.2017.02.793
Abstract: OBJECTIVE To investigate the effects of different strontium ranelate (SrR) doses alone or in combination with low-intensity and high-frequency mechanical vibration (MV) on articular cartilage in ovariectomized rats. DESIGN Fifty 6-month-old female Wistar rats underwent… read more here.
Keywords: ovariectomized rats; mechanical vibration; vibration; strontium ranelate ... See more keywords
Cynomorium songaricum prevents bone resorption in ovariectomized rats through RANKL/RANK/TRAF6 mediated suppression of PI3K/AKT and NF‐&kgr;B pathways
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DOI: 10.1016/j.lfs.2018.08.008
Abstract: Aim: Cynomorium songaricum Rupr., an edible and important Traditional Chinese medicine has long been used in folk for treatment of kidney deficiency, was chosen to estimate the antiosteoporotic activity and underlying molecular mechanism on rats… read more here.
Keywords: rankl rank; pi3k; ovariectomized rats; bone resorption ... See more keywords
Extracellular regulated kinase 5 mediates osteoporosis through modulating viability and apoptosis of osteoblasts in ovariectomized rats
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DOI: 10.1042/bsr20190432
Abstract: Postmenopausal osteoporosis is a common condition characterized by the increase and activation of osteoclasts. The present study aimed to investigate the effects of extracellular signal-regulated kinase (ERK) 5 (ERK-5) on postmenopausal osteoporosis by regulating the… read more here.
Keywords: ovariectomized rats; postmenopausal osteoporosis; erk; viability ... See more keywords
Effect of rosuvastatin on spatial learning, memory, and anxiety-like behaviour in ovariectomized rats
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DOI: 10.1080/01443615.2022.2112024
Abstract: Abstract The effect of rosuvastatin (Ros) on cognitive function and anxiety-like behaviour in ovariectomized rats were evaluated. Eighteen female Wistar rats (218–310 g, 6–8 months old) were allocated into sham (n = 6), ovariectomy (Ovx, n = 6) or Ovx + Ros (up… read more here.
Keywords: like behaviour; anxiety like; ovariectomized rats; effect ... See more keywords
Effects of Moderate-Intensity Aerobic Exercise on Estrogen Levels and Bone Mineral Density in Ovariectomized Rats
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DOI: 10.1080/07435800.2025.2484198
Abstract: ABSTRACT Objective This study aimed to explore the effects of moderate-intensity aerobic exercise on estrogen levels and bone density density (BMD) in ovariectomized rats. Methods The sham-operated (SHAM), ovariectomized sedentary (OVX), and ovariectomized exercise (OVX + EX)… read more here.
Keywords: moderate intensity; intensity aerobic; density; exercise ... See more keywords